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pubmed-article:20888840pubmed:abstractTextGanoderma lucidum, a traditional Chinese medicine, is well known as a modulator of functions of the immune system as well as an anti-tumour agent. However, its active compounds and their molecular mechanisms of action are not well established. GLIS, a proteoglycan isolated from the fruiting body of G. lucidum, stimulates directly the activation of B lymphocytes. In this work, the immunoactivation capacities of GLIS as well as its anti-tumour effect were investigated in vitro and in vivo.lld:pubmed
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pubmed-article:20888840pubmed:authorpubmed-author:ZhangJingsong...lld:pubmed
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pubmed-article:20888840pubmed:copyrightInfoCopyright © 2010 Elsevier Inc. All rights reserved.lld:pubmed
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pubmed-article:20888840pubmed:articleTitleGLIS, a bioactive proteoglycan fraction from Ganoderma lucidum, displays anti-tumour activity by increasing both humoral and cellular immune response.lld:pubmed
pubmed-article:20888840pubmed:affiliationInstitut für Biochemie und Molekularbiologie, CBF, Charité-Universitätsmedizin Berlin, Germany.lld:pubmed
pubmed-article:20888840pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:20888840pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed