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pubmed-article:20887888pubmed:abstractTextAneuploidy, or an abnormal number of chromosomes, adversely affects cell growth, but it is also linked with cancer and tumorigenesis. Now, Torres et al. (2010) help to resolve this paradox by demonstrating that aneuploid yeast cells can evolve mutations in the proteasome protein degradation pathway that alleviate imbalances in protein production and increase the cell's proliferative capacities.lld:pubmed
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pubmed-article:20887888pubmed:statusPubMed-not-MEDLINElld:pubmed
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pubmed-article:20887888pubmed:issn1097-4172lld:pubmed
pubmed-article:20887888pubmed:authorpubmed-author:ClevelandDon...lld:pubmed
pubmed-article:20887888pubmed:authorpubmed-author:CetinBulentBlld:pubmed
pubmed-article:20887888pubmed:copyrightInfoCopyright © 2010 Elsevier Inc. All rights reserved.lld:pubmed
pubmed-article:20887888pubmed:issnTypeElectroniclld:pubmed
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pubmed-article:20887888pubmed:volume143lld:pubmed
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pubmed-article:20887888pubmed:pagination27-9lld:pubmed
pubmed-article:20887888pubmed:dateRevised2011-10-3lld:pubmed
pubmed-article:20887888pubmed:year2010lld:pubmed
pubmed-article:20887888pubmed:articleTitleHow to survive aneuploidy.lld:pubmed
pubmed-article:20887888pubmed:affiliationLudwig Institute for Cancer Research and Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA.lld:pubmed
pubmed-article:20887888pubmed:publicationTypeJournal Articlelld:pubmed
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