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pubmed-article:20880956pubmed:abstractTextThe Illumina BeadArray is a popular platform for profiling DNA methylation, an important epigenetic event associated with gene silencing and chromosomal instability. However, current approaches rely on an arbitrary detection P-value cutoff for excluding probes and samples from subsequent analysis as a quality control step, which results in missing observations and information loss. It is desirable to have an approach that incorporates the whole data, but accounts for the different quality of individual observations.lld:pubmed
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pubmed-article:20880956pubmed:authorpubmed-author:ZhouXinXlld:pubmed
pubmed-article:20880956pubmed:authorpubmed-author:WangSijianSlld:pubmed
pubmed-article:20880956pubmed:authorpubmed-author:ChuHaitaoHlld:pubmed
pubmed-article:20880956pubmed:authorpubmed-author:KuanPei FenPFlld:pubmed
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pubmed-article:20880956pubmed:year2010lld:pubmed
pubmed-article:20880956pubmed:articleTitleA statistical framework for Illumina DNA methylation arrays.lld:pubmed
pubmed-article:20880956pubmed:affiliationDepartment of Biostatistics, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599, USA. pfkuan@bios.unc.edulld:pubmed
pubmed-article:20880956pubmed:publicationTypeJournal Articlelld:pubmed
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