| pubmed-article:20855113 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:20855113 | lifeskim:mentions | umls-concept:C0007634 | lld:lifeskim |
| pubmed-article:20855113 | lifeskim:mentions | umls-concept:C0035820 | lld:lifeskim |
| pubmed-article:20855113 | lifeskim:mentions | umls-concept:C0027627 | lld:lifeskim |
| pubmed-article:20855113 | lifeskim:mentions | umls-concept:C0037083 | lld:lifeskim |
| pubmed-article:20855113 | lifeskim:mentions | umls-concept:C1332688 | lld:lifeskim |
| pubmed-article:20855113 | lifeskim:mentions | umls-concept:C1710082 | lld:lifeskim |
| pubmed-article:20855113 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:20855113 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:20855113 | pubmed:dateCreated | 2010-12-20 | lld:pubmed |
| pubmed-article:20855113 | pubmed:abstractText | Our previous research has revealed that binding of the chemokine CCL25 to the CCR9 provides chemotactic cues guiding leukemic cells to specific tissues and organs. The RhoA-ROCK pathway might be involved in cancer migration. The purpose of this study was to explore the role of the RhoA-ROCK-MLC axis in leukemic cell migration following exposure to CCL25. The results showed that CCL25 could increase the amount of the GTPase RhoA and activate MLC in MOLT4 cells in a time-dependent manner. C3 exoenzyme and Y-27632 could block MOLT4 cell migration and chemotaxis. Thus, the RhoA-ROCK-MLC axis might play an important role in MOLT4 cell metastasis induced by CCL25. | lld:pubmed |
| pubmed-article:20855113 | pubmed:language | eng | lld:pubmed |
| pubmed-article:20855113 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20855113 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:20855113 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20855113 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20855113 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20855113 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20855113 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20855113 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:20855113 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:20855113 | pubmed:issn | 1873-5835 | lld:pubmed |
| pubmed-article:20855113 | pubmed:author | pubmed-author:LaraR CRC | lld:pubmed |
| pubmed-article:20855113 | pubmed:author | pubmed-author:ZhangLiL | lld:pubmed |
| pubmed-article:20855113 | pubmed:author | pubmed-author:HuYiY | lld:pubmed |
| pubmed-article:20855113 | pubmed:author | pubmed-author:ZhanWangW | lld:pubmed |
| pubmed-article:20855113 | pubmed:author | pubmed-author:ZhangQiupingQ | lld:pubmed |
| pubmed-article:20855113 | pubmed:author | pubmed-author:PRAGJ JJJ | lld:pubmed |
| pubmed-article:20855113 | pubmed:author | pubmed-author:LiuDongyingD | lld:pubmed |
| pubmed-article:20855113 | pubmed:author | pubmed-author:ZhouBeibeiB | lld:pubmed |
| pubmed-article:20855113 | pubmed:author | pubmed-author:TongXiaolingX | lld:pubmed |
| pubmed-article:20855113 | pubmed:author | pubmed-author:YuBeibeiB | lld:pubmed |
| pubmed-article:20855113 | pubmed:author | pubmed-author:WuRanranR | lld:pubmed |
| pubmed-article:20855113 | pubmed:author | pubmed-author:DingQianshanQ | lld:pubmed |
| pubmed-article:20855113 | pubmed:copyrightInfo | Copyright © 2010 Elsevier Ltd. All rights reserved. | lld:pubmed |
| pubmed-article:20855113 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:20855113 | pubmed:volume | 35 | lld:pubmed |
| pubmed-article:20855113 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:20855113 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:20855113 | pubmed:pagination | 103-9 | lld:pubmed |
| pubmed-article:20855113 | pubmed:meshHeading | pubmed-meshheading:20855113... | lld:pubmed |
| pubmed-article:20855113 | pubmed:meshHeading | pubmed-meshheading:20855113... | lld:pubmed |
| pubmed-article:20855113 | pubmed:meshHeading | pubmed-meshheading:20855113... | lld:pubmed |
| pubmed-article:20855113 | pubmed:meshHeading | pubmed-meshheading:20855113... | lld:pubmed |
| pubmed-article:20855113 | pubmed:meshHeading | pubmed-meshheading:20855113... | lld:pubmed |
| pubmed-article:20855113 | pubmed:meshHeading | pubmed-meshheading:20855113... | lld:pubmed |
| pubmed-article:20855113 | pubmed:year | 2011 | lld:pubmed |
| pubmed-article:20855113 | pubmed:articleTitle | Role of Rho-ROCK signaling in MOLT4 cells metastasis induced by CCL25. | lld:pubmed |
| pubmed-article:20855113 | pubmed:affiliation | Department of Immunology, College of Basic Medical Science, Wuhan University, 185 Donghu Road, Wuhan, 430071 Hubei, China. | lld:pubmed |
| pubmed-article:20855113 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:20855113 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
