Source:http://linkedlifedata.com/resource/pubmed/id/20818652
Cancer 2011 Jan 15 117 2 421-34
General Info
Abstract
The authors demonstrated previously that the combination of topotecan (TPT) and carboplatin (CBP) was more effective than current chemotherapeutic combinations used to treat retinoblastoma in an orthotopic xenograft model. However, systemic coadministration of these agents is not ideal, because both agents cause dose-limiting myelosuppression in children.
PMID
20818652
Publication types
Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural