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pubmed-article:20705965pubmed:abstractTextIt was postulated that in patients with membranous nephropathy (MN), four weekly doses of Rituximab (RTX) would result in more effective B cell depletion, a higher remission rate, and maintaining the same safety profile compared with patients treated with RTX dosed at 1 g every 2 weeks. This hypothesis was supported by previous pharmacokinetic (PK) analysis showing that RTX levels in the two-dose regimen were 50% lower compared with nonproteinuric patients, which could potentially result in undertreatment.lld:pubmed
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pubmed-article:20705965pubmed:articleTitleRituximab therapy in idiopathic membranous nephropathy: a 2-year study.lld:pubmed
pubmed-article:20705965pubmed:affiliationDivision of Nephrology and Hypertension, Mayo Clinic College of Medicine, Rochester, MN 55901, USA. fervenza.fernando@mayo.edulld:pubmed
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