| pubmed-article:20705401 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:20705401 | lifeskim:mentions | umls-concept:C0032659 | lld:lifeskim |
| pubmed-article:20705401 | lifeskim:mentions | umls-concept:C1556094 | lld:lifeskim |
| pubmed-article:20705401 | lifeskim:mentions | umls-concept:C0033975 | lld:lifeskim |
| pubmed-article:20705401 | lifeskim:mentions | umls-concept:C0332281 | lld:lifeskim |
| pubmed-article:20705401 | lifeskim:mentions | umls-concept:C1335671 | lld:lifeskim |
| pubmed-article:20705401 | lifeskim:mentions | umls-concept:C0384853 | lld:lifeskim |
| pubmed-article:20705401 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:20705401 | pubmed:dateCreated | 2010-12-21 | lld:pubmed |
| pubmed-article:20705401 | pubmed:abstractText | Altered serotonergic neural transmission is hypothesized to be a susceptibility factor for psychotic disorders such as schizophrenia. The serotonin 6 (5-HT6) receptor is therapeutically targeted by several second generation antipsychotics, such as clozapine and olanzapine, and d-amphetamine-induced hyperactivity in rats is corrected with the use of a selective 5-HT6 receptor antagonist. In addition, the disrupted prepulse inhibition induced by d-amphetamine or phencyclidine was restored by 5-HT6 receptor antagonist in an animal study using rats. These animal models were considered to reflect the positive symptoms of schizophrenia, and the above evidence suggests that altered 5-HT6 receptors are involved in the pathophysiology of psychotic disorders. The symptoms of methamphetamine (METH)-induced psychosis are similar to those of paranoid type schizophrenia. Therefore, we conducted an analysis of the association of the 5-HT6 gene (HTR6) with METH-induced psychosis. | lld:pubmed |
| pubmed-article:20705401 | pubmed:language | eng | lld:pubmed |
| pubmed-article:20705401 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20705401 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:20705401 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20705401 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20705401 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20705401 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20705401 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:20705401 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:20705401 | pubmed:issn | 1879-0046 | lld:pubmed |
| pubmed-article:20705401 | pubmed:author | pubmed-author:YamadaMitsuhi... | lld:pubmed |
| pubmed-article:20705401 | pubmed:author | pubmed-author:IyoMasaomiM | lld:pubmed |
| pubmed-article:20705401 | pubmed:author | pubmed-author:OzakiNorioN | lld:pubmed |
| pubmed-article:20705401 | pubmed:author | pubmed-author:InadaToshiyaT | lld:pubmed |
| pubmed-article:20705401 | pubmed:author | pubmed-author:SoraIchiroI | lld:pubmed |
| pubmed-article:20705401 | pubmed:author | pubmed-author:UjikeHiroshiH | lld:pubmed |
| pubmed-article:20705401 | pubmed:author | pubmed-author:UchimuraNaohi... | lld:pubmed |
| pubmed-article:20705401 | pubmed:author | pubmed-author:KitajimaTsuyo... | lld:pubmed |
| pubmed-article:20705401 | pubmed:author | pubmed-author:IwataNakaoN | lld:pubmed |
| pubmed-article:20705401 | pubmed:author | pubmed-author:KawashimaKuni... | lld:pubmed |
| pubmed-article:20705401 | pubmed:author | pubmed-author:NaitohHiroshi... | lld:pubmed |
| pubmed-article:20705401 | pubmed:author | pubmed-author:KishiTaroT | lld:pubmed |
| pubmed-article:20705401 | pubmed:author | pubmed-author:OkochiTomoT | lld:pubmed |
| pubmed-article:20705401 | pubmed:author | pubmed-author:FukuoYasuhisa... | lld:pubmed |
| pubmed-article:20705401 | pubmed:copyrightInfo | Crown Copyright © 2010. Published by Elsevier Ireland Ltd. All rights reserved. | lld:pubmed |
| pubmed-article:20705401 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:20705401 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:20705401 | pubmed:volume | 113 | lld:pubmed |
| pubmed-article:20705401 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:20705401 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:20705401 | pubmed:pagination | 1-7 | lld:pubmed |
| pubmed-article:20705401 | pubmed:meshHeading | pubmed-meshheading:20705401... | lld:pubmed |
| pubmed-article:20705401 | pubmed:meshHeading | pubmed-meshheading:20705401... | lld:pubmed |
| pubmed-article:20705401 | pubmed:meshHeading | pubmed-meshheading:20705401... | lld:pubmed |
| pubmed-article:20705401 | pubmed:meshHeading | pubmed-meshheading:20705401... | lld:pubmed |
| pubmed-article:20705401 | pubmed:meshHeading | pubmed-meshheading:20705401... | lld:pubmed |
| pubmed-article:20705401 | pubmed:meshHeading | pubmed-meshheading:20705401... | lld:pubmed |
| pubmed-article:20705401 | pubmed:meshHeading | pubmed-meshheading:20705401... | lld:pubmed |
| pubmed-article:20705401 | pubmed:meshHeading | pubmed-meshheading:20705401... | lld:pubmed |
| pubmed-article:20705401 | pubmed:meshHeading | pubmed-meshheading:20705401... | lld:pubmed |
| pubmed-article:20705401 | pubmed:meshHeading | pubmed-meshheading:20705401... | lld:pubmed |
| pubmed-article:20705401 | pubmed:meshHeading | pubmed-meshheading:20705401... | lld:pubmed |
| pubmed-article:20705401 | pubmed:meshHeading | pubmed-meshheading:20705401... | lld:pubmed |
| pubmed-article:20705401 | pubmed:meshHeading | pubmed-meshheading:20705401... | lld:pubmed |
| pubmed-article:20705401 | pubmed:year | 2011 | lld:pubmed |
| pubmed-article:20705401 | pubmed:articleTitle | Serotonin 6 receptor gene is associated with methamphetamine-induced psychosis in a Japanese population. | lld:pubmed |
| pubmed-article:20705401 | pubmed:affiliation | Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Aichi, Japan. tarok@fujita-hu.ac.jp | lld:pubmed |
| pubmed-article:20705401 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:20705401 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:3362 | entrezgene:pubmed | pubmed-article:20705401 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:20705401 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:20705401 | lld:entrezgene |
