Treatment and prevention of bone metastases is a major problem in patients with cancer. New treatment of bone metastases are needed to maintain the quality of life of our patients with metastastic bone disease. In addition, promising preliminary results suggest that bone-directed therapies may be able to prevent both skeletal and extraskeletal metastases
Department of Medicine, Division of Hematology/Oncology, MS Hershey Medical Center of the Pennsylvania State University, Hershey, Pennsylvania 17033, USA. alipton@hmc.psu.edu
