| pubmed-article:20691510 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:20691510 | lifeskim:mentions | umls-concept:C0035647 | lld:lifeskim |
| pubmed-article:20691510 | lifeskim:mentions | umls-concept:C0036311 | lld:lifeskim |
| pubmed-article:20691510 | lifeskim:mentions | umls-concept:C0596913 | lld:lifeskim |
| pubmed-article:20691510 | lifeskim:mentions | umls-concept:C0682906 | lld:lifeskim |
| pubmed-article:20691510 | lifeskim:mentions | umls-concept:C1521991 | lld:lifeskim |
| pubmed-article:20691510 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:20691510 | lifeskim:mentions | umls-concept:C1522290 | lld:lifeskim |
| pubmed-article:20691510 | lifeskim:mentions | umls-concept:C0220825 | lld:lifeskim |
| pubmed-article:20691510 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:20691510 | lifeskim:mentions | umls-concept:C2266864 | lld:lifeskim |
| pubmed-article:20691510 | lifeskim:mentions | umls-concept:C0205460 | lld:lifeskim |
| pubmed-article:20691510 | pubmed:issue | 10 | lld:pubmed |
| pubmed-article:20691510 | pubmed:dateCreated | 2010-8-30 | lld:pubmed |
| pubmed-article:20691510 | pubmed:abstractText | Six transition metal compounds of Schiff base ligands were evaluated for the inhibitory activity on jack bean urease, of which compounds 2-6 were determined by single crystal X-ray analysis. It was found that copper(II) complexes 1 and 4 showed strong inhibitory activity against jack bean urease (IC(50) = 0.52 and 0.46 microM), compared with acetohydroxamic acid (IC(50) = 42.12 microM) as a positive reference. Cobalt(II), nickel(II) and zinc(II) compounds also exhibited potent inhibitory activity (IC(50) = 3.88-25.20 microM). A docking analysis using the AUTODOCK 4.0 program could explain the inhibitory activities of 1 and 4 against urease. | lld:pubmed |
| pubmed-article:20691510 | pubmed:language | eng | lld:pubmed |
| pubmed-article:20691510 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20691510 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:20691510 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20691510 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20691510 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20691510 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20691510 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20691510 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:20691510 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:20691510 | pubmed:issn | 1768-3254 | lld:pubmed |
| pubmed-article:20691510 | pubmed:author | pubmed-author:ZhangXianX | lld:pubmed |
| pubmed-article:20691510 | pubmed:author | pubmed-author:ZhuHai-LiangH... | lld:pubmed |
| pubmed-article:20691510 | pubmed:author | pubmed-author:WuChenC | lld:pubmed |
| pubmed-article:20691510 | pubmed:author | pubmed-author:ZengQingfuQ | lld:pubmed |
| pubmed-article:20691510 | pubmed:author | pubmed-author:LiYuguangY | lld:pubmed |
| pubmed-article:20691510 | pubmed:author | pubmed-author:CuiYongmingY | lld:pubmed |
| pubmed-article:20691510 | pubmed:copyrightInfo | Copyright (c) 2010 Elsevier Masson SAS. All rights reserved. | lld:pubmed |
| pubmed-article:20691510 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:20691510 | pubmed:volume | 45 | lld:pubmed |
| pubmed-article:20691510 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:20691510 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:20691510 | pubmed:pagination | 4473-8 | lld:pubmed |
| pubmed-article:20691510 | pubmed:meshHeading | pubmed-meshheading:20691510... | lld:pubmed |
| pubmed-article:20691510 | pubmed:meshHeading | pubmed-meshheading:20691510... | lld:pubmed |
| pubmed-article:20691510 | pubmed:meshHeading | pubmed-meshheading:20691510... | lld:pubmed |
| pubmed-article:20691510 | pubmed:meshHeading | pubmed-meshheading:20691510... | lld:pubmed |
| pubmed-article:20691510 | pubmed:meshHeading | pubmed-meshheading:20691510... | lld:pubmed |
| pubmed-article:20691510 | pubmed:meshHeading | pubmed-meshheading:20691510... | lld:pubmed |
| pubmed-article:20691510 | pubmed:meshHeading | pubmed-meshheading:20691510... | lld:pubmed |
| pubmed-article:20691510 | pubmed:meshHeading | pubmed-meshheading:20691510... | lld:pubmed |
| pubmed-article:20691510 | pubmed:meshHeading | pubmed-meshheading:20691510... | lld:pubmed |
| pubmed-article:20691510 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:20691510 | pubmed:articleTitle | Synthesis, molecular docking and biological evaluation of Schiff base transition metal complexes as potential urease inhibitors. | lld:pubmed |
| pubmed-article:20691510 | pubmed:affiliation | Engineering Research Center for Clean Production of Textile Printing, Ministry of Education, Wuhan Textile University, Wuhan 430073, People's Republic of China. | lld:pubmed |
| pubmed-article:20691510 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:20691510 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
