pubmed-article:206891 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:206891 | lifeskim:mentions | umls-concept:C0038975 | lld:lifeskim |
pubmed-article:206891 | lifeskim:mentions | umls-concept:C0035696 | lld:lifeskim |
pubmed-article:206891 | pubmed:issue | 3 | lld:pubmed |
pubmed-article:206891 | pubmed:dateCreated | 1978-7-15 | lld:pubmed |
pubmed-article:206891 | pubmed:abstractText | Biochemical methods are presented for determining the structure of spliced RNAs present in cells at low concentrations. Two cytoplasmic spliced viral RNAs were detected in CV-1 cells during the early phase of simian virus 40 (SV40) infection. One is 2200 nucleotides in length and is composed of two parts, 330 and 1900 nucleotides, mapping from approximately 0.67 to approximately 0.60 and from approximately 0.54 to approximately 0.14, respectively, on the standard viral map. The other is 2500 nucleotides long and also is composed of two parts, 630 and 1900 nucleotides mapping from approximately 0.67 to approximately 0.54 and from approximately 0.54 to approximately 0.14, respectively. Correlation of the structure of these mRNAs with the structure of the early SV40 proteins, small T antigen (17,000 daltons) and large T antigen (90,000 daltons), determined by others suggests that: (i) translation of the 2500-nucleotide mRNA yields small T antigen; (ii) translation of the 2200-nucleotide mRNA proceeds through the splice point in the RNA to produce large T antigen (and thus large T antigen is encoded in two separate regions of the viral genome); and (iii) the DNA sequences between approximately 0.67 and approximately 0.60 present in both mRNAs are translated in the same reading frame in both mRNAs to yield two separate gene products that have the same NH(2)-terminal sequence. Therefore, expression of the early SV40 genes is partially controlled at the level of splicing of RNAs. | lld:pubmed |
pubmed-article:206891 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:206891 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:206891 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:206891 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:206891 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:206891 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:206891 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:206891 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:206891 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:206891 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:206891 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:206891 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:206891 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:206891 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:206891 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:206891 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:206891 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:206891 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:206891 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:206891 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:206891 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:206891 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:206891 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:206891 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:206891 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:206891 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:206891 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:206891 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:206891 | pubmed:language | eng | lld:pubmed |
pubmed-article:206891 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:206891 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:206891 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:206891 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:206891 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:206891 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:206891 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:206891 | pubmed:month | Mar | lld:pubmed |
pubmed-article:206891 | pubmed:issn | 0027-8424 | lld:pubmed |
pubmed-article:206891 | pubmed:author | pubmed-author:SharpP APA | lld:pubmed |
pubmed-article:206891 | pubmed:author | pubmed-author:BerkA JAJ | lld:pubmed |
pubmed-article:206891 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:206891 | pubmed:volume | 75 | lld:pubmed |
pubmed-article:206891 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:206891 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:206891 | pubmed:pagination | 1274-8 | lld:pubmed |
pubmed-article:206891 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
pubmed-article:206891 | pubmed:meshHeading | pubmed-meshheading:206891-M... | lld:pubmed |
pubmed-article:206891 | pubmed:meshHeading | pubmed-meshheading:206891-V... | lld:pubmed |
pubmed-article:206891 | pubmed:meshHeading | pubmed-meshheading:206891-R... | lld:pubmed |
pubmed-article:206891 | pubmed:meshHeading | pubmed-meshheading:206891-C... | lld:pubmed |
pubmed-article:206891 | pubmed:meshHeading | pubmed-meshheading:206891-S... | lld:pubmed |
pubmed-article:206891 | pubmed:meshHeading | pubmed-meshheading:206891-G... | lld:pubmed |
pubmed-article:206891 | pubmed:meshHeading | pubmed-meshheading:206891-A... | lld:pubmed |
pubmed-article:206891 | pubmed:meshHeading | pubmed-meshheading:206891-G... | lld:pubmed |
pubmed-article:206891 | pubmed:meshHeading | pubmed-meshheading:206891-A... | lld:pubmed |
pubmed-article:206891 | pubmed:meshHeading | pubmed-meshheading:206891-C... | lld:pubmed |
pubmed-article:206891 | pubmed:year | 1978 | lld:pubmed |
pubmed-article:206891 | pubmed:articleTitle | Spliced early mRNAs of simian virus 40. | lld:pubmed |
pubmed-article:206891 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:206891 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
entrez-gene:1489525 | entrezgene:pubmed | pubmed-article:206891 | lld:entrezgene |
entrez-gene:1489526 | entrezgene:pubmed | pubmed-article:206891 | lld:entrezgene |
entrez-gene:1489527 | entrezgene:pubmed | pubmed-article:206891 | lld:entrezgene |
entrez-gene:1489528 | entrezgene:pubmed | pubmed-article:206891 | lld:entrezgene |
entrez-gene:1489529 | entrezgene:pubmed | pubmed-article:206891 | lld:entrezgene |
entrez-gene:1489530 | entrezgene:pubmed | pubmed-article:206891 | lld:entrezgene |
entrez-gene:1489531 | entrezgene:pubmed | pubmed-article:206891 | lld:entrezgene |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:206891 | lld:pubmed |