pubmed-article:206646 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:206646 | lifeskim:mentions | umls-concept:C0018895 | lld:lifeskim |
pubmed-article:206646 | lifeskim:mentions | umls-concept:C0086574 | lld:lifeskim |
pubmed-article:206646 | lifeskim:mentions | umls-concept:C1510411 | lld:lifeskim |
pubmed-article:206646 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
pubmed-article:206646 | pubmed:issue | 4 | lld:pubmed |
pubmed-article:206646 | pubmed:dateCreated | 1978-7-15 | lld:pubmed |
pubmed-article:206646 | pubmed:abstractText | Abelson murine leukemia virus (A-MuLV)-transformed fibroblast nonproducer cells were used to prepare A-MuLV stocks containing a number of different helper viruses. The oncogenicity of the A-MuLV stocks was tested by animal inoculation and their ability to transform normal mouse bone marrow cells was measured in vitro. All of the A-MuLV stocks transformed fibroblast cells efficiently. However, only A-MuLV stocks prepared with helper viruses that are highly oncogenic were efficient in vivo and in vitro in hematopoietic cell transformation. In addition, inefficient helpers did not establish a stable infection in lymphoid nonproducer cells. Thus, helper virus has a more central role in lymphoid cell transformation than in fibroblast cell transformation. | lld:pubmed |
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pubmed-article:206646 | pubmed:language | eng | lld:pubmed |
pubmed-article:206646 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:206646 | pubmed:citationSubset | AIM | lld:pubmed |
pubmed-article:206646 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:206646 | pubmed:month | Apr | lld:pubmed |
pubmed-article:206646 | pubmed:issn | 0022-1007 | lld:pubmed |
pubmed-article:206646 | pubmed:author | pubmed-author:BaltimoreDD | lld:pubmed |
pubmed-article:206646 | pubmed:author | pubmed-author:RosenbergNN | lld:pubmed |
pubmed-article:206646 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:206646 | pubmed:day | 1 | lld:pubmed |
pubmed-article:206646 | pubmed:volume | 147 | lld:pubmed |
pubmed-article:206646 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:206646 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:206646 | pubmed:pagination | 1126-41 | lld:pubmed |
pubmed-article:206646 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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pubmed-article:206646 | pubmed:year | 1978 | lld:pubmed |
pubmed-article:206646 | pubmed:articleTitle | The effect of helper virus on Abelson virus-induced transformation of lymphoid cells. | lld:pubmed |
pubmed-article:206646 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:206646 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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