| pubmed-article:20660325 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:20660325 | lifeskim:mentions | umls-concept:C0220847 | lld:lifeskim |
| pubmed-article:20660325 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:20660325 | lifeskim:mentions | umls-concept:C1622186 | lld:lifeskim |
| pubmed-article:20660325 | lifeskim:mentions | umls-concept:C0004358 | lld:lifeskim |
| pubmed-article:20660325 | lifeskim:mentions | umls-concept:C0205210 | lld:lifeskim |
| pubmed-article:20660325 | lifeskim:mentions | umls-concept:C0205460 | lld:lifeskim |
| pubmed-article:20660325 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:20660325 | pubmed:dateCreated | 2010-7-27 | lld:pubmed |
| pubmed-article:20660325 | pubmed:abstractText | The purpose of this study was to evaluate the relationship between serum filamentous (F)-actin antibody titers and severity of hepatitis present in hepatitis C virus (HCV)-infected patients. Liver biopsy samples from 18 HCV monoinfected and 20 HCV-HIV coinfected patients were graded with respect to the degree of hepatitis activity and intensity of plasma cell infiltration using MUM-1 and CD138 immunostains. Of the 38 HCV-infected patients, 6 (16%) had F-actin antibody titers in excess of 30 enzyme-linked immunosorbent assay units. We found a positive trend between serum F-actin antibody levels and the mean number of plasma cells present in the portal tracts of patients with HCV infection (r = 0.31; P = .06) and a significant association between these factors in HCV-HIV coinfected patients (r = 0.64; P = .002). Our data suggest that elevated serum F-actin antibody titers are commonly encountered in HCV-infected patients and may reflect more active inflammation in liver biopsy samples, similar to autoimmune hepatitis. | lld:pubmed |
| pubmed-article:20660325 | pubmed:language | eng | lld:pubmed |
| pubmed-article:20660325 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20660325 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:20660325 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20660325 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20660325 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20660325 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:20660325 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:20660325 | pubmed:issn | 1943-7722 | lld:pubmed |
| pubmed-article:20660325 | pubmed:author | pubmed-author:YantissRhonda... | lld:pubmed |
| pubmed-article:20660325 | pubmed:author | pubmed-author:TalalAndrew... | lld:pubmed |
| pubmed-article:20660325 | pubmed:author | pubmed-author:JacobsonIraI | lld:pubmed |
| pubmed-article:20660325 | pubmed:author | pubmed-author:ZhouXi KXK | lld:pubmed |
| pubmed-article:20660325 | pubmed:author | pubmed-author:WaxDavid MDM | lld:pubmed |
| pubmed-article:20660325 | pubmed:author | pubmed-author:HudackoRachel... | lld:pubmed |
| pubmed-article:20660325 | pubmed:author | pubmed-author:AlvarezGustav... | lld:pubmed |
| pubmed-article:20660325 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:20660325 | pubmed:volume | 134 | lld:pubmed |
| pubmed-article:20660325 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:20660325 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:20660325 | pubmed:pagination | 228-34 | lld:pubmed |
| pubmed-article:20660325 | pubmed:meshHeading | pubmed-meshheading:20660325... | lld:pubmed |
| pubmed-article:20660325 | pubmed:meshHeading | pubmed-meshheading:20660325... | lld:pubmed |
| pubmed-article:20660325 | pubmed:meshHeading | pubmed-meshheading:20660325... | lld:pubmed |
| pubmed-article:20660325 | pubmed:meshHeading | pubmed-meshheading:20660325... | lld:pubmed |
| pubmed-article:20660325 | pubmed:meshHeading | pubmed-meshheading:20660325... | lld:pubmed |
| pubmed-article:20660325 | pubmed:meshHeading | pubmed-meshheading:20660325... | lld:pubmed |
| pubmed-article:20660325 | pubmed:meshHeading | pubmed-meshheading:20660325... | lld:pubmed |
| pubmed-article:20660325 | pubmed:meshHeading | pubmed-meshheading:20660325... | lld:pubmed |
| pubmed-article:20660325 | pubmed:meshHeading | pubmed-meshheading:20660325... | lld:pubmed |
| pubmed-article:20660325 | pubmed:meshHeading | pubmed-meshheading:20660325... | lld:pubmed |
| pubmed-article:20660325 | pubmed:meshHeading | pubmed-meshheading:20660325... | lld:pubmed |
| pubmed-article:20660325 | pubmed:meshHeading | pubmed-meshheading:20660325... | lld:pubmed |
| pubmed-article:20660325 | pubmed:meshHeading | pubmed-meshheading:20660325... | lld:pubmed |
| pubmed-article:20660325 | pubmed:meshHeading | pubmed-meshheading:20660325... | lld:pubmed |
| pubmed-article:20660325 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:20660325 | pubmed:articleTitle | Clinical and biologic importance of F-actin autoantibodies in HCV monoinfected and HCV-HIV coinfected patients. | lld:pubmed |
| pubmed-article:20660325 | pubmed:affiliation | Dept. of Pathology and Laboratory Medicine, Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA. | lld:pubmed |
| pubmed-article:20660325 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:20660325 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
