| pubmed-article:20659452 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:20659452 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:20659452 | lifeskim:mentions | umls-concept:C0013227 | lld:lifeskim |
| pubmed-article:20659452 | lifeskim:mentions | umls-concept:C0030567 | lld:lifeskim |
| pubmed-article:20659452 | lifeskim:mentions | umls-concept:C0003635 | lld:lifeskim |
| pubmed-article:20659452 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:20659452 | pubmed:dateCreated | 2010-9-13 | lld:pubmed |
| pubmed-article:20659452 | pubmed:abstractText | Impairment of hand dexterity in Parkinson's disease (PD) is usually attributed to bradykinesia. Recently, behavioral studies illustrated that decreased dexterity might also be due to limb-kinetic apraxia (LkA), as demonstrated by impaired performance in a coin rotation task. Here, we provide a first investigation on whether functional magnetic resonance imaging (fMRI) may reveal specific brain activation patterns for PD patients with impaired performance in a coin rotation task. We compared coin rotation as an apraxia task to simple finger tapping as a bradykinesia task in ten PD patients OFF medication and matched healthy controls. In addition to a tendency for general overactivation, PD patients showed a perirolandic dissociation with precentral overactivation and postcentral underactivation. This finding significantly separated PD patients from healthy controls. | lld:pubmed |
| pubmed-article:20659452 | pubmed:language | eng | lld:pubmed |
| pubmed-article:20659452 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20659452 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:20659452 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:20659452 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:20659452 | pubmed:issn | 1090-2430 | lld:pubmed |
| pubmed-article:20659452 | pubmed:author | pubmed-author:GeisslerAA | lld:pubmed |
| pubmed-article:20659452 | pubmed:author | pubmed-author:KlingelHH | lld:pubmed |
| pubmed-article:20659452 | pubmed:author | pubmed-author:LehrnerJJ | lld:pubmed |
| pubmed-article:20659452 | pubmed:author | pubmed-author:TrattnigSS | lld:pubmed |
| pubmed-article:20659452 | pubmed:author | pubmed-author:GruberSS | lld:pubmed |
| pubmed-article:20659452 | pubmed:author | pubmed-author:AuffEE | lld:pubmed |
| pubmed-article:20659452 | pubmed:author | pubmed-author:BeisteinerRR | lld:pubmed |
| pubmed-article:20659452 | pubmed:author | pubmed-author:RathJJ | lld:pubmed |
| pubmed-article:20659452 | pubmed:author | pubmed-author:PirkerWW | lld:pubmed |
| pubmed-article:20659452 | pubmed:author | pubmed-author:PusswaldGG | lld:pubmed |
| pubmed-article:20659452 | pubmed:author | pubmed-author:HaubenbergerD... | lld:pubmed |
| pubmed-article:20659452 | pubmed:author | pubmed-author:FokiTT | lld:pubmed |
| pubmed-article:20659452 | pubmed:author | pubmed-author:SteinkellnerT... | lld:pubmed |
| pubmed-article:20659452 | pubmed:author | pubmed-author:HoellingerII | lld:pubmed |
| pubmed-article:20659452 | pubmed:copyrightInfo | Copyright © 2010 Elsevier Inc. All rights reserved. | lld:pubmed |
| pubmed-article:20659452 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:20659452 | pubmed:volume | 225 | lld:pubmed |
| pubmed-article:20659452 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:20659452 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:20659452 | pubmed:pagination | 416-22 | lld:pubmed |
| pubmed-article:20659452 | pubmed:meshHeading | pubmed-meshheading:20659452... | lld:pubmed |
| pubmed-article:20659452 | pubmed:meshHeading | pubmed-meshheading:20659452... | lld:pubmed |
| pubmed-article:20659452 | pubmed:meshHeading | pubmed-meshheading:20659452... | lld:pubmed |
| pubmed-article:20659452 | pubmed:meshHeading | pubmed-meshheading:20659452... | lld:pubmed |
| pubmed-article:20659452 | pubmed:meshHeading | pubmed-meshheading:20659452... | lld:pubmed |
| pubmed-article:20659452 | pubmed:meshHeading | pubmed-meshheading:20659452... | lld:pubmed |
| pubmed-article:20659452 | pubmed:meshHeading | pubmed-meshheading:20659452... | lld:pubmed |
| pubmed-article:20659452 | pubmed:meshHeading | pubmed-meshheading:20659452... | lld:pubmed |
| pubmed-article:20659452 | pubmed:meshHeading | pubmed-meshheading:20659452... | lld:pubmed |
| pubmed-article:20659452 | pubmed:meshHeading | pubmed-meshheading:20659452... | lld:pubmed |
| pubmed-article:20659452 | pubmed:meshHeading | pubmed-meshheading:20659452... | lld:pubmed |
| pubmed-article:20659452 | pubmed:meshHeading | pubmed-meshheading:20659452... | lld:pubmed |
| pubmed-article:20659452 | pubmed:meshHeading | pubmed-meshheading:20659452... | lld:pubmed |
| pubmed-article:20659452 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:20659452 | pubmed:articleTitle | FMRI correlates of apraxia in Parkinson's disease patients OFF medication. | lld:pubmed |
| pubmed-article:20659452 | pubmed:affiliation | Department of Neurology, Medical University of Vienna, Vienna, Austria. thomas.foki@meduniwien.ac.at | lld:pubmed |
| pubmed-article:20659452 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:20659452 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
