| pubmed-article:2065027 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2065027 | lifeskim:mentions | umls-concept:C0032105 | lld:lifeskim |
| pubmed-article:2065027 | lifeskim:mentions | umls-concept:C0020557 | lld:lifeskim |
| pubmed-article:2065027 | lifeskim:mentions | umls-concept:C0242970 | lld:lifeskim |
| pubmed-article:2065027 | lifeskim:mentions | umls-concept:C0441994 | lld:lifeskim |
| pubmed-article:2065027 | lifeskim:mentions | umls-concept:C0443602 | lld:lifeskim |
| pubmed-article:2065027 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:2065027 | pubmed:dateCreated | 1991-8-14 | lld:pubmed |
| pubmed-article:2065027 | pubmed:abstractText | A sudden increase in dietary carbohydrate invariably increases the plasma levels of very low density lipoprotein (VLDL) and triglyceride. The present studies were designed to test the hypothesis that dietary carbohydrate-induced hypertriglyceridemia need not occur. In the first study we fed gradually increasing amounts of carbohydrate and gradually decreasing amounts of fat to eight subjects. The usual American diet (40% fat, 45% carbohydrate, and 15% protein) was followed in sequence by four diets in a phased regimen, the carbohydrate increasing by 5% of total calories and the fat content decreasing by 5% for each dietary period. In the last dietary period (phase 4), 20% of the energy was in the form of fat and 65% in the form of carbohydrates; the cholesterol content was 100 mg/day. Throughout the study, plasma triglyceride and VLDL triglyceride levels did not change significantly. The plasma total and low density lipoprotein (LDL) cholesterol levels were greatly reduced, by 15% and 22%, respectively (p = 0.004). Plasma high density lipoprotein (HDL) cholesterol levels decreased concomitantly. In the second study, after a washout period six of the subjects were initially fed the phase 4 high-carbohydrate diet for a 10-day period. The plasma triglyceride concentration increased over baseline levels by 47%, and VLDL triglyceride levels increased by 73%. We conclude that although a sudden increase in dietary carbohydrate increases the plasma triglyceride level, patients gradually introduced to a high-carbohydrate, low-fat diet may achieve a significant reduction of plasma total and LDL cholesterol without developing carbohydrate-induced hypertriglyceridemia. | lld:pubmed |
| pubmed-article:2065027 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2065027 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2065027 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2065027 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2065027 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2065027 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2065027 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2065027 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2065027 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2065027 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2065027 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2065027 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2065027 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2065027 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2065027 | pubmed:issn | 1049-8834 | lld:pubmed |
| pubmed-article:2065027 | pubmed:author | pubmed-author:ConnorW EWE | lld:pubmed |
| pubmed-article:2065027 | pubmed:author | pubmed-author:ConnorS LSL | lld:pubmed |
| pubmed-article:2065027 | pubmed:author | pubmed-author:UllmannDD | lld:pubmed |
| pubmed-article:2065027 | pubmed:author | pubmed-author:FlavellD PDP | lld:pubmed |
| pubmed-article:2065027 | pubmed:author | pubmed-author:HatcherL FLF | lld:pubmed |
| pubmed-article:2065027 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2065027 | pubmed:volume | 11 | lld:pubmed |
| pubmed-article:2065027 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2065027 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2065027 | pubmed:pagination | 1059-67 | lld:pubmed |
| pubmed-article:2065027 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:2065027 | pubmed:meshHeading | pubmed-meshheading:2065027-... | lld:pubmed |
| pubmed-article:2065027 | pubmed:meshHeading | pubmed-meshheading:2065027-... | lld:pubmed |
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| pubmed-article:2065027 | pubmed:meshHeading | pubmed-meshheading:2065027-... | lld:pubmed |
| pubmed-article:2065027 | pubmed:meshHeading | pubmed-meshheading:2065027-... | lld:pubmed |
| pubmed-article:2065027 | pubmed:meshHeading | pubmed-meshheading:2065027-... | lld:pubmed |
| pubmed-article:2065027 | pubmed:meshHeading | pubmed-meshheading:2065027-... | lld:pubmed |
| pubmed-article:2065027 | pubmed:meshHeading | pubmed-meshheading:2065027-... | lld:pubmed |
| pubmed-article:2065027 | pubmed:meshHeading | pubmed-meshheading:2065027-... | lld:pubmed |
| pubmed-article:2065027 | pubmed:meshHeading | pubmed-meshheading:2065027-... | lld:pubmed |
| pubmed-article:2065027 | pubmed:articleTitle | Will a high-carbohydrate, low-fat diet lower plasma lipids and lipoproteins without producing hypertriglyceridemia? | lld:pubmed |
| pubmed-article:2065027 | pubmed:affiliation | Department of Medicine, Oregon Health Sciences University, Portland 97201-3098. | lld:pubmed |
| pubmed-article:2065027 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2065027 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:2065027 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
