| pubmed-article:20638088 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:20638088 | lifeskim:mentions | umls-concept:C0995574 | lld:lifeskim |
| pubmed-article:20638088 | lifeskim:mentions | umls-concept:C0040549 | lld:lifeskim |
| pubmed-article:20638088 | lifeskim:mentions | umls-concept:C1511790 | lld:lifeskim |
| pubmed-article:20638088 | lifeskim:mentions | umls-concept:C0027964 | lld:lifeskim |
| pubmed-article:20638088 | pubmed:issue | 7-12 | lld:pubmed |
| pubmed-article:20638088 | pubmed:dateCreated | 2010-8-25 | lld:pubmed |
| pubmed-article:20638088 | pubmed:abstractText | Marine pelagic cyanobacteria Trichodesmium are widespread in the New Caledonia lagoon. Blooms of these Oscillatoriales are suspected to be a potential source of toxins in the ciguatera food chain and were previously reported to contain certain types of paralysing toxins. In the present study, toxicity experiments were conducted on lipid- and water-soluble extracts of freeze-dried samples of these cyanobacteria. Lipid-soluble fractions revealed a ciguatoxin-like activity in both in vivo (mouse bioassay) and in vitro (mouse neuroblastoma cells assay and receptor binding assay using tritiated brevetoxin-3) assays. The water-soluble fractions tested on mice exhibited neurotoxicity with paralytic symptoms. These toxicities have also been observed with benthic filamentous cyanobacteria within the Oscillatoriales order, also collected in New Caledonia. This study provides an unprecedented evidence of the toxicity of Trichodesmium species from the New Caledonia lagoon. This survey also demonstrates the possible role of these cyanobacteria in ciguatera fish poisoning. | lld:pubmed |
| pubmed-article:20638088 | pubmed:language | eng | lld:pubmed |
| pubmed-article:20638088 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20638088 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:20638088 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20638088 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20638088 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20638088 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20638088 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20638088 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20638088 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:20638088 | pubmed:issn | 1879-3363 | lld:pubmed |
| pubmed-article:20638088 | pubmed:author | pubmed-author:PauillacSerge... | lld:pubmed |
| pubmed-article:20638088 | pubmed:author | pubmed-author:LaurentDomini... | lld:pubmed |
| pubmed-article:20638088 | pubmed:author | pubmed-author:ChinainMireil... | lld:pubmed |
| pubmed-article:20638088 | pubmed:author | pubmed-author:DariusH... | lld:pubmed |
| pubmed-article:20638088 | pubmed:author | pubmed-author:KerbratAnne-S... | lld:pubmed |
| pubmed-article:20638088 | pubmed:copyrightInfo | Copyright (c) 2010 Elsevier Ltd. All rights reserved. | lld:pubmed |
| pubmed-article:20638088 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:20638088 | pubmed:volume | 61 | lld:pubmed |
| pubmed-article:20638088 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:20638088 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:20638088 | pubmed:pagination | 360-6 | lld:pubmed |
| pubmed-article:20638088 | pubmed:meshHeading | pubmed-meshheading:20638088... | lld:pubmed |
| pubmed-article:20638088 | pubmed:meshHeading | pubmed-meshheading:20638088... | lld:pubmed |
| pubmed-article:20638088 | pubmed:meshHeading | pubmed-meshheading:20638088... | lld:pubmed |
| pubmed-article:20638088 | pubmed:meshHeading | pubmed-meshheading:20638088... | lld:pubmed |
| pubmed-article:20638088 | pubmed:meshHeading | pubmed-meshheading:20638088... | lld:pubmed |
| pubmed-article:20638088 | pubmed:meshHeading | pubmed-meshheading:20638088... | lld:pubmed |
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| pubmed-article:20638088 | pubmed:meshHeading | pubmed-meshheading:20638088... | lld:pubmed |
| pubmed-article:20638088 | pubmed:meshHeading | pubmed-meshheading:20638088... | lld:pubmed |
| pubmed-article:20638088 | pubmed:meshHeading | pubmed-meshheading:20638088... | lld:pubmed |
| pubmed-article:20638088 | pubmed:meshHeading | pubmed-meshheading:20638088... | lld:pubmed |
| pubmed-article:20638088 | pubmed:meshHeading | pubmed-meshheading:20638088... | lld:pubmed |
| pubmed-article:20638088 | pubmed:meshHeading | pubmed-meshheading:20638088... | lld:pubmed |
| pubmed-article:20638088 | pubmed:meshHeading | pubmed-meshheading:20638088... | lld:pubmed |
| pubmed-article:20638088 | pubmed:meshHeading | pubmed-meshheading:20638088... | lld:pubmed |
| pubmed-article:20638088 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:20638088 | pubmed:articleTitle | Detection of ciguatoxin-like and paralysing toxins in Trichodesmium spp. from New Caledonia lagoon. | lld:pubmed |
| pubmed-article:20638088 | pubmed:affiliation | Laboratoire Pharmacochimie des Substances Naturelles et Pharmacophores Redox, Université de Toulouse, UPS, UMR152, 118 Route de Narbonne, F-31062 Toulouse Cedex 9, France. | lld:pubmed |
| pubmed-article:20638088 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:20638088 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:20638088 | lld:pubmed |
