| pubmed-article:20631309 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:20631309 | lifeskim:mentions | umls-concept:C1332717 | lld:lifeskim |
| pubmed-article:20631309 | lifeskim:mentions | umls-concept:C1706438 | lld:lifeskim |
| pubmed-article:20631309 | lifeskim:mentions | umls-concept:C0039194 | lld:lifeskim |
| pubmed-article:20631309 | lifeskim:mentions | umls-concept:C0085358 | lld:lifeskim |
| pubmed-article:20631309 | lifeskim:mentions | umls-concept:C0072980 | lld:lifeskim |
| pubmed-article:20631309 | lifeskim:mentions | umls-concept:C1704632 | lld:lifeskim |
| pubmed-article:20631309 | lifeskim:mentions | umls-concept:C0871261 | lld:lifeskim |
| pubmed-article:20631309 | lifeskim:mentions | umls-concept:C1306235 | lld:lifeskim |
| pubmed-article:20631309 | lifeskim:mentions | umls-concept:C1413244 | lld:lifeskim |
| pubmed-article:20631309 | lifeskim:mentions | umls-concept:C2698600 | lld:lifeskim |
| pubmed-article:20631309 | lifeskim:mentions | umls-concept:C2911692 | lld:lifeskim |
| pubmed-article:20631309 | lifeskim:mentions | umls-concept:C1706817 | lld:lifeskim |
| pubmed-article:20631309 | lifeskim:mentions | umls-concept:C0152060 | lld:lifeskim |
| pubmed-article:20631309 | lifeskim:mentions | umls-concept:C0205154 | lld:lifeskim |
| pubmed-article:20631309 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:20631309 | pubmed:dateCreated | 2010-8-5 | lld:pubmed |
| pubmed-article:20631309 | pubmed:abstractText | Recent evidence demonstrating that exposure to rapamycin during viral infection increased the quantity and quality of Ag-specific T cells poses an intriguing paradox, because rapamycin is used in transplantation to dampen, rather than enhance, donor-reactive T cell responses. In this report, we compared the effects of rapamycin on the Ag-specific T cell response to a bacterial infection versus a transplant. Using a transgenic system in which the Ag and the responding T cell population were identical in both cases, we observed that treatment with rapamycin augmented the Ag-specific T cell response to a pathogen, whereas it failed to do so when the Ag was presented in the context of a transplant. These results suggest that the environment in which an Ag is presented alters the influence of rapamycin on Ag-specific T cell expansion and highlights a fundamental difference between Ag presented by an infectious agent as compared with an allograft. | lld:pubmed |
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| pubmed-article:20631309 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20631309 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20631309 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20631309 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20631309 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20631309 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20631309 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20631309 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20631309 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20631309 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20631309 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20631309 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20631309 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20631309 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20631309 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20631309 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20631309 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20631309 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20631309 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20631309 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20631309 | pubmed:language | eng | lld:pubmed |
| pubmed-article:20631309 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20631309 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:20631309 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20631309 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20631309 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20631309 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20631309 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:20631309 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:20631309 | pubmed:issn | 1550-6606 | lld:pubmed |
| pubmed-article:20631309 | pubmed:author | pubmed-author:LarsenChristi... | lld:pubmed |
| pubmed-article:20631309 | pubmed:author | pubmed-author:AhmedRafiR | lld:pubmed |
| pubmed-article:20631309 | pubmed:author | pubmed-author:KirkAllan DAD | lld:pubmed |
| pubmed-article:20631309 | pubmed:author | pubmed-author:ArakiKoichiK | lld:pubmed |
| pubmed-article:20631309 | pubmed:author | pubmed-author:FordMandy LML | lld:pubmed |
| pubmed-article:20631309 | pubmed:author | pubmed-author:RobertsonJenn... | lld:pubmed |
| pubmed-article:20631309 | pubmed:author | pubmed-author:WagenerMaylen... | lld:pubmed |
| pubmed-article:20631309 | pubmed:author | pubmed-author:FerrerIvana... | lld:pubmed |
| pubmed-article:20631309 | pubmed:author | pubmed-author:TurnerAlexa... | lld:pubmed |
| pubmed-article:20631309 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:20631309 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:20631309 | pubmed:volume | 185 | lld:pubmed |
| pubmed-article:20631309 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:20631309 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:20631309 | pubmed:pagination | 2004-8 | lld:pubmed |
| pubmed-article:20631309 | pubmed:dateRevised | 2011-9-26 | lld:pubmed |
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| pubmed-article:20631309 | pubmed:meshHeading | pubmed-meshheading:20631309... | lld:pubmed |
| pubmed-article:20631309 | pubmed:meshHeading | pubmed-meshheading:20631309... | lld:pubmed |
| pubmed-article:20631309 | pubmed:meshHeading | pubmed-meshheading:20631309... | lld:pubmed |
| pubmed-article:20631309 | pubmed:meshHeading | pubmed-meshheading:20631309... | lld:pubmed |
| pubmed-article:20631309 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:20631309 | pubmed:articleTitle | Cutting edge: Rapamycin augments pathogen-specific but not graft-reactive CD8+ T cell responses. | lld:pubmed |
| pubmed-article:20631309 | pubmed:affiliation | Emory Transplant Center, Emory University, Atlanta, GA 30322, USA. | lld:pubmed |
| pubmed-article:20631309 | pubmed:publicationType | Journal Article | lld:pubmed |
