pubmed-article:20627934 | pubmed:abstractText | Several transcription factors are essential to pancreatic islet ?-cell development, proliferation, and activity, including MafA and MafB. However, MafA and MafB are distinct from others in regard to temporal and islet cell expression pattern, with ?-cells affected by MafB only during development and exclusively by MafA in the adult. Our aim was to define the functional relationship between these closely related activators to the ?-cell. | lld:pubmed |