| pubmed-article:20621474 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:20621474 | lifeskim:mentions | umls-concept:C0003209 | lld:lifeskim |
| pubmed-article:20621474 | lifeskim:mentions | umls-concept:C0301869 | lld:lifeskim |
| pubmed-article:20621474 | lifeskim:mentions | umls-concept:C0055753 | lld:lifeskim |
| pubmed-article:20621474 | lifeskim:mentions | umls-concept:C1455182 | lld:lifeskim |
| pubmed-article:20621474 | pubmed:issue | 16 | lld:pubmed |
| pubmed-article:20621474 | pubmed:dateCreated | 2010-7-27 | lld:pubmed |
| pubmed-article:20621474 | pubmed:abstractText | A morroniside cinnamic acid conjugate was prepared and evaluated on E-selectin mediated cell-cell adhesion as an important role in inflammatory processes. 7-O-Cinnamoylmorroniside exhibited excellent anti-inflammatory activity (IC(50)=49.3 microM) by inhibiting the expression of E-selectin; further, it was more active than another cinnamic-acid-conjugated iridoid glycoside (harpagoside; IC(50)=88.2 microM), 7-O-methylmorroniside, and morroniside itself. As a result, 7-O-cinnamoylmorroniside was observed to be a potent inhibitor of TNF-alpha-induced E-selectin expression. | lld:pubmed |
| pubmed-article:20621474 | pubmed:language | eng | lld:pubmed |
| pubmed-article:20621474 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20621474 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:20621474 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20621474 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20621474 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20621474 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20621474 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20621474 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20621474 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20621474 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20621474 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20621474 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:20621474 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:20621474 | pubmed:issn | 1464-3405 | lld:pubmed |
| pubmed-article:20621474 | pubmed:author | pubmed-author:KoketsuMamoru... | lld:pubmed |
| pubmed-article:20621474 | pubmed:author | pubmed-author:MatsushitaKen... | lld:pubmed |
| pubmed-article:20621474 | pubmed:author | pubmed-author:HagiwaraMakot... | lld:pubmed |
| pubmed-article:20621474 | pubmed:author | pubmed-author:SunghwaFortun... | lld:pubmed |
| pubmed-article:20621474 | pubmed:author | pubmed-author:NinomiyaMasay... | lld:pubmed |
| pubmed-article:20621474 | pubmed:author | pubmed-author:TakedaYoshino... | lld:pubmed |
| pubmed-article:20621474 | pubmed:author | pubmed-author:TanigawaNaomi... | lld:pubmed |
| pubmed-article:20621474 | pubmed:copyrightInfo | 2010 Elsevier Ltd. All rights reserved. | lld:pubmed |
| pubmed-article:20621474 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:20621474 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:20621474 | pubmed:volume | 20 | lld:pubmed |
| pubmed-article:20621474 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:20621474 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:20621474 | pubmed:pagination | 4855-7 | lld:pubmed |
| pubmed-article:20621474 | pubmed:meshHeading | pubmed-meshheading:20621474... | lld:pubmed |
| pubmed-article:20621474 | pubmed:meshHeading | pubmed-meshheading:20621474... | lld:pubmed |
| pubmed-article:20621474 | pubmed:meshHeading | pubmed-meshheading:20621474... | lld:pubmed |
| pubmed-article:20621474 | pubmed:meshHeading | pubmed-meshheading:20621474... | lld:pubmed |
| pubmed-article:20621474 | pubmed:meshHeading | pubmed-meshheading:20621474... | lld:pubmed |
| pubmed-article:20621474 | pubmed:meshHeading | pubmed-meshheading:20621474... | lld:pubmed |
| pubmed-article:20621474 | pubmed:meshHeading | pubmed-meshheading:20621474... | lld:pubmed |
| pubmed-article:20621474 | pubmed:meshHeading | pubmed-meshheading:20621474... | lld:pubmed |
| pubmed-article:20621474 | pubmed:meshHeading | pubmed-meshheading:20621474... | lld:pubmed |
| pubmed-article:20621474 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:20621474 | pubmed:articleTitle | Morroniside cinnamic acid conjugate as an anti-inflammatory agent. | lld:pubmed |
| pubmed-article:20621474 | pubmed:affiliation | Department of Chemistry, Faculty of Engineering, Gifu University, 1-1 Yanagido, Gifu 501-1193, Japan. | lld:pubmed |
| pubmed-article:20621474 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:20621474 | lld:chembl |
