20603072

Source:http://linkedlifedata.com/resource/pubmed/id/20603072

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Subject	Predicate	Object	Context
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pubmed-article:20603072	lifeskim:mentions	umls-concept:C0007610	lld:lifeskim
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pubmed-article:20603072	lifeskim:mentions	umls-concept:C1521991	lld:lifeskim
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pubmed-article:20603072	pubmed:issue	1	lld:pubmed
pubmed-article:20603072	pubmed:dateCreated	2010-7-6	lld:pubmed
pubmed-article:20603072	pubmed:abstractText	The abundant nuclear enzyme PARP-1, a multifunctional regulator of chromatin structure, transcription, and genomic integrity, plays key roles in a wide variety of processes in the nucleus. Recent studies have begun to connect the molecular functions of PARP-1 to specific physiological and pathological outcomes, many of which can be altered by an expanding array of chemical inhibitors of PARP enzymatic activity.	lld:pubmed
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