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pubmed-article:20585130pubmed:abstractTextIn vitro activity of tebipenem, a new oral carbapenem antibiotic, against clinical Haemophilus influenzae isolates was compared with those of 8 reference agents. Isolates were classified into 6 resistance classes after PCR identification of beta-lactamase genes and ftsI gene mutations. For all isolates, the minimal concentration at which 90% of isolates were inhibited was lower for tebipenem than for the reference oral antibiotics, except for cefditoren. Tebipenem also showed excellent bactericidal activity against beta-lactamase-nonproducing, ampicillin-resistant isolates.lld:pubmed
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pubmed-article:20585130pubmed:dateRevised2011-7-25lld:pubmed
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pubmed-article:20585130pubmed:articleTitleIn vitro activity of tebipenem, a new oral carbapenem antibiotic, against beta-lactamase-nonproducing, ampicillin-resistant Haemophilus influenzae.lld:pubmed
pubmed-article:20585130pubmed:affiliationLaboratory of Molecular Epidemiology for Infectious Agents, Kitasato Institute for Life Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan.lld:pubmed
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