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pubmed-article:20560575pubmed:abstractTextThe efficient Suzuki cross-coupling of pyrazoline nonaflates with organoboron reagents was achieved to afford diverse 3-substituted-2-pyrazolines in excellent yield. The nonaflates displayed improved reactivity over the corresponding triflates and smoothly coupled to a variety of aryl- and heteroarylboronic acids. This process and its broad scope constitute a rapid, divergent strategy for the synthesis of elaborated 2-pyrazolines that are not readily obtained via conventional methods.lld:pubmed
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pubmed-article:20560575pubmed:authorpubmed-author:WilsonKevin...lld:pubmed
pubmed-article:20560575pubmed:authorpubmed-author:GrimmJonathan...lld:pubmed
pubmed-article:20560575pubmed:authorpubmed-author:WitterDavid...lld:pubmed
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pubmed-article:20560575pubmed:articleTitleA divergent approach to the synthesis of 3-substituted-2-pyrazolines: Suzuki cross-coupling of 3-sulfonyloxy-2-pyrazolines.lld:pubmed
pubmed-article:20560575pubmed:affiliationDepartment of Chemistry, Merck Research Laboratories, Boston, Massachusetts 02115, USA. jonathan_grimm@merck.comlld:pubmed
pubmed-article:20560575pubmed:publicationTypeJournal Articlelld:pubmed