A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release.

Source:http://linkedlifedata.com/resource/pubmed/id/20547845

Proc. Natl. Acad. Sci. U.S.A. 2010 Jun 29 107 26 11942-7

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20547845