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pubmed-article:20535393pubmed:dateCreated2010-6-10lld:pubmed
pubmed-article:20535393pubmed:abstractTextThe immunostimulating activities of mucilage fraction from yam were investigated. The proliferation of BSA-primed lymph node cells was enhanced between 4.1- to 10.9-fold compare to control, when cultured with 1 to 25 microg/mL of yam-mucilage fraction. It showed strong immunopotentiating activity than ginseng extract and as remarkable as Bifidobacterium adolescentis M101-4 known as a positive immunostimulator. Mitogenicity to lymph node cells was fully induced by concanavalin A and lipopolysaccharide. The proliferation of splenocytes and Peyer's patch cells was enhanced between 5.0- to 14.1-fold and 2.4- to 6.4-fold, respectively, when cultured with 1 to 25 microg/mL of yam-mucilage fraction. It enhanced the production of cytokines such as tumor necrosis factor-alpha and IL-6 in the culture of RAW 264.7 macrophage cells. In the culture of lipopolysaccharide-stimulated RAW 264.7 cells, production of cytokines was as similar as compared to controls. In unstimulated RAW 264.7 cells, both tumor necrosis factor-alpha and IL-6 production were enhanced between 15.6- to 60.1-fold and 2.3- to 9.1-fold, respectively. Mucilage fraction from yam is expected to be a safe immunopotentiator to maintain the host immunity and develop a physiologically functional food.lld:pubmed
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pubmed-article:20535393pubmed:statusPubMed-not-MEDLINElld:pubmed
pubmed-article:20535393pubmed:issn2005-6168lld:pubmed
pubmed-article:20535393pubmed:authorpubmed-author:LeeJong-HwaJHlld:pubmed
pubmed-article:20535393pubmed:authorpubmed-author:KweonDae-Hyuk...lld:pubmed
pubmed-article:20535393pubmed:authorpubmed-author:JangCheol-Min...lld:pubmed
pubmed-article:20535393pubmed:issnTypeElectroniclld:pubmed
pubmed-article:20535393pubmed:volume1lld:pubmed
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pubmed-article:20535393pubmed:pagination94-9lld:pubmed
pubmed-article:20535393pubmed:year2007lld:pubmed
pubmed-article:20535393pubmed:articleTitleEffect of mucilage from yam on activation of lymphocytic immune cells.lld:pubmed
pubmed-article:20535393pubmed:affiliationSchool of Bioresource Science, Andong National University, Andong, Gyeongbuk 760-749, Korea.lld:pubmed
pubmed-article:20535393pubmed:publicationTypeJournal Articlelld:pubmed