pubmed-article:20535393 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:20535393 | lifeskim:mentions | umls-concept:C0007634 | lld:lifeskim |
pubmed-article:20535393 | lifeskim:mentions | umls-concept:C0331683 | lld:lifeskim |
pubmed-article:20535393 | lifeskim:mentions | umls-concept:C0024264 | lld:lifeskim |
pubmed-article:20535393 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
pubmed-article:20535393 | lifeskim:mentions | umls-concept:C0439662 | lld:lifeskim |
pubmed-article:20535393 | lifeskim:mentions | umls-concept:C0026679 | lld:lifeskim |
pubmed-article:20535393 | lifeskim:mentions | umls-concept:C2349971 | lld:lifeskim |
pubmed-article:20535393 | lifeskim:mentions | umls-concept:C1879547 | lld:lifeskim |
pubmed-article:20535393 | pubmed:issue | 2 | lld:pubmed |
pubmed-article:20535393 | pubmed:dateCreated | 2010-6-10 | lld:pubmed |
pubmed-article:20535393 | pubmed:abstractText | The immunostimulating activities of mucilage fraction from yam were investigated. The proliferation of BSA-primed lymph node cells was enhanced between 4.1- to 10.9-fold compare to control, when cultured with 1 to 25 microg/mL of yam-mucilage fraction. It showed strong immunopotentiating activity than ginseng extract and as remarkable as Bifidobacterium adolescentis M101-4 known as a positive immunostimulator. Mitogenicity to lymph node cells was fully induced by concanavalin A and lipopolysaccharide. The proliferation of splenocytes and Peyer's patch cells was enhanced between 5.0- to 14.1-fold and 2.4- to 6.4-fold, respectively, when cultured with 1 to 25 microg/mL of yam-mucilage fraction. It enhanced the production of cytokines such as tumor necrosis factor-alpha and IL-6 in the culture of RAW 264.7 macrophage cells. In the culture of lipopolysaccharide-stimulated RAW 264.7 cells, production of cytokines was as similar as compared to controls. In unstimulated RAW 264.7 cells, both tumor necrosis factor-alpha and IL-6 production were enhanced between 15.6- to 60.1-fold and 2.3- to 9.1-fold, respectively. Mucilage fraction from yam is expected to be a safe immunopotentiator to maintain the host immunity and develop a physiologically functional food. | lld:pubmed |
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pubmed-article:20535393 | pubmed:language | eng | lld:pubmed |
pubmed-article:20535393 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20535393 | pubmed:status | PubMed-not-MEDLINE | lld:pubmed |
pubmed-article:20535393 | pubmed:issn | 2005-6168 | lld:pubmed |
pubmed-article:20535393 | pubmed:author | pubmed-author:LeeJong-HwaJH | lld:pubmed |
pubmed-article:20535393 | pubmed:author | pubmed-author:KweonDae-Hyuk... | lld:pubmed |
pubmed-article:20535393 | pubmed:author | pubmed-author:JangCheol-Min... | lld:pubmed |
pubmed-article:20535393 | pubmed:issnType | Electronic | lld:pubmed |
pubmed-article:20535393 | pubmed:volume | 1 | lld:pubmed |
pubmed-article:20535393 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:20535393 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:20535393 | pubmed:pagination | 94-9 | lld:pubmed |
pubmed-article:20535393 | pubmed:year | 2007 | lld:pubmed |
pubmed-article:20535393 | pubmed:articleTitle | Effect of mucilage from yam on activation of lymphocytic immune cells. | lld:pubmed |
pubmed-article:20535393 | pubmed:affiliation | School of Bioresource Science, Andong National University, Andong, Gyeongbuk 760-749, Korea. | lld:pubmed |
pubmed-article:20535393 | pubmed:publicationType | Journal Article | lld:pubmed |