| pubmed-article:20534261 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:20534261 | lifeskim:mentions | umls-concept:C0019163 | lld:lifeskim |
| pubmed-article:20534261 | lifeskim:mentions | umls-concept:C0023911 | lld:lifeskim |
| pubmed-article:20534261 | lifeskim:mentions | umls-concept:C1274040 | lld:lifeskim |
| pubmed-article:20534261 | lifeskim:mentions | umls-concept:C1623038 | lld:lifeskim |
| pubmed-article:20534261 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:20534261 | pubmed:dateCreated | 2010-6-10 | lld:pubmed |
| pubmed-article:20534261 | pubmed:abstractText | Hepatitis C virus (HCV) recurrence after orthotopic liver transplantation (OLT) is almost universal; cirrhosis develops in up to 30% of cases. Currently there is interest in the midterm outcomes of HCV patients with concomitant hepatitis B virus (HBV) infection among OLT recipients. We therefore retrospectively analyzed our database of patients who underwent OLT for HCV-HBV-related cirrhosis. Between April 1992 and December 2008, 350 patients underwent OLT, including 20 (5.7%) transplanted for HBV-HCV cirrhosis. We assessed patient and graft survivals at 1 and 5 years, as well as the progression of fibrosis. Protocol liver biopsies were available yearly after OLT. The survival curves were analyzed by the Kaplan-Meier approach and chronic hepatitis evaluated according to the Ishak scoring system. At a median follow-up of 68.4 +/- 53 months, the 1- and 5-year patient and graft survival rates were 80% and 70%, respectively. The 5-year fibrosis progression rate was 0.17 +/- 0.08 units of fibrosis. The only patient who developed histologic cirrhosis within 10 years of follow-up showed a lamivudine-resistant HBV recurrence. Patients transplanted for HBV-HCV coinfection showed a lower fibrosis progression rate compared with HCV monoinfected subjects. | lld:pubmed |
| pubmed-article:20534261 | pubmed:language | eng | lld:pubmed |
| pubmed-article:20534261 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20534261 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:20534261 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20534261 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20534261 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20534261 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20534261 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20534261 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20534261 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20534261 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:20534261 | pubmed:month | May | lld:pubmed |
| pubmed-article:20534261 | pubmed:issn | 1873-2623 | lld:pubmed |
| pubmed-article:20534261 | pubmed:author | pubmed-author:TotiLL | lld:pubmed |
| pubmed-article:20534261 | pubmed:author | pubmed-author:AngelicoMM | lld:pubmed |
| pubmed-article:20534261 | pubmed:author | pubmed-author:BregaAA | lld:pubmed |
| pubmed-article:20534261 | pubmed:author | pubmed-author:AngelicoRR | lld:pubmed |
| pubmed-article:20534261 | pubmed:author | pubmed-author:TisoneGG | lld:pubmed |
| pubmed-article:20534261 | pubmed:author | pubmed-author:SforzaDD | lld:pubmed |
| pubmed-article:20534261 | pubmed:author | pubmed-author:Di PaoloDD | lld:pubmed |
| pubmed-article:20534261 | pubmed:author | pubmed-author:ManziaT MTM | lld:pubmed |
| pubmed-article:20534261 | pubmed:copyrightInfo | Copyright (c) 2010. Published by Elsevier Inc. | lld:pubmed |
| pubmed-article:20534261 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:20534261 | pubmed:volume | 42 | lld:pubmed |
| pubmed-article:20534261 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:20534261 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:20534261 | pubmed:pagination | 1200-3 | lld:pubmed |
| pubmed-article:20534261 | pubmed:meshHeading | pubmed-meshheading:20534261... | lld:pubmed |
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| pubmed-article:20534261 | pubmed:meshHeading | pubmed-meshheading:20534261... | lld:pubmed |
| pubmed-article:20534261 | pubmed:meshHeading | pubmed-meshheading:20534261... | lld:pubmed |
| pubmed-article:20534261 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:20534261 | pubmed:articleTitle | Liver transplantation for hepatitis B and C virus-related cirrhosis: mid-term results. | lld:pubmed |
| pubmed-article:20534261 | pubmed:affiliation | Transplant Unit, Department of Surgery, University of Rome Tor Vergata, Rome, Italy. tomanzia@libero.it | lld:pubmed |
| pubmed-article:20534261 | pubmed:publicationType | Journal Article | lld:pubmed |
