| pubmed-article:20522536 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:20522536 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:20522536 | lifeskim:mentions | umls-concept:C0003250 | lld:lifeskim |
| pubmed-article:20522536 | lifeskim:mentions | umls-concept:C0730345 | lld:lifeskim |
| pubmed-article:20522536 | lifeskim:mentions | umls-concept:C0011847 | lld:lifeskim |
| pubmed-article:20522536 | lifeskim:mentions | umls-concept:C0920321 | lld:lifeskim |
| pubmed-article:20522536 | pubmed:issue | 8 | lld:pubmed |
| pubmed-article:20522536 | pubmed:dateCreated | 2010-8-9 | lld:pubmed |
| pubmed-article:20522536 | pubmed:abstractText | This report summarizes the first phase 1 trial treating patients with microalbuminuric diabetic kidney disease (DKD) using FG-3019, a human monoclonal antibody to connective tissue growth factor (CTGF). CTGF is critically involved in processes of progressive fibrosis, including DKD. This phase 1, open-label, dose-escalation trial evaluated safety, pharmacokinetics, and possible therapeutic effects of FG-3019 on albuminuria, proteinuria, and tubular proteins. | lld:pubmed |
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| pubmed-article:20522536 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:20522536 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:20522536 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:20522536 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:20522536 | pubmed:issn | 1555-905X | lld:pubmed |
| pubmed-article:20522536 | pubmed:author | pubmed-author:Arauz-Pacheco... | lld:pubmed |
| pubmed-article:20522536 | pubmed:author | pubmed-author:WilliamsMark... | lld:pubmed |
| pubmed-article:20522536 | pubmed:author | pubmed-author:LiDongxiaD | lld:pubmed |
| pubmed-article:20522536 | pubmed:author | pubmed-author:AdlerSharon... | lld:pubmed |
| pubmed-article:20522536 | pubmed:author | pubmed-author:SewellK LeaKL | lld:pubmed |
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| pubmed-article:20522536 | pubmed:author | pubmed-author:LeeTysonT | lld:pubmed |
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| pubmed-article:20522536 | pubmed:author | pubmed-author:UrquillaPedro... | lld:pubmed |
| pubmed-article:20522536 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:20522536 | pubmed:volume | 5 | lld:pubmed |
| pubmed-article:20522536 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:20522536 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:20522536 | pubmed:pagination | 1420-8 | lld:pubmed |
| pubmed-article:20522536 | pubmed:dateRevised | 2011-8-9 | lld:pubmed |
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| pubmed-article:20522536 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:20522536 | pubmed:articleTitle | Phase 1 study of anti-CTGF monoclonal antibody in patients with diabetes and microalbuminuria. | lld:pubmed |
| pubmed-article:20522536 | pubmed:affiliation | Division of Nephrology and Hypertension, Los Angeles BioMedical Research Institute, Torrance, California 90502, USA. sadler@labiomed.org | lld:pubmed |
| pubmed-article:20522536 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:20522536 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:20522536 | pubmed:publicationType | Clinical Trial, Phase I | lld:pubmed |
| entrez-gene:1490 | entrezgene:pubmed | pubmed-article:20522536 | lld:entrezgene |
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