| pubmed-article:20519263 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:20519263 | lifeskim:mentions | umls-concept:C0006675 | lld:lifeskim |
| pubmed-article:20519263 | lifeskim:mentions | umls-concept:C0007144 | lld:lifeskim |
| pubmed-article:20519263 | lifeskim:mentions | umls-concept:C0162859 | lld:lifeskim |
| pubmed-article:20519263 | lifeskim:mentions | umls-concept:C0205042 | lld:lifeskim |
| pubmed-article:20519263 | lifeskim:mentions | umls-concept:C0043100 | lld:lifeskim |
| pubmed-article:20519263 | lifeskim:mentions | umls-concept:C1280412 | lld:lifeskim |
| pubmed-article:20519263 | lifeskim:mentions | umls-concept:C0004083 | lld:lifeskim |
| pubmed-article:20519263 | lifeskim:mentions | umls-concept:C0443199 | lld:lifeskim |
| pubmed-article:20519263 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
| pubmed-article:20519263 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:20519263 | pubmed:dateCreated | 2010-7-12 | lld:pubmed |
| pubmed-article:20519263 | pubmed:abstractText | Change and fluctuation in body mass index (BMI; weight (kg)/height (m)(2)) may be associated differently with coronary artery calcification (CAC) than with carotid artery intima-media thickness (IMT). The authors analyzed data on 2,243 participants in the Coronary Artery Risk Development in Young Adults (CARDIA) Study, initially aged 18-30 years, who were examined every 2-5 years over a 20-year period (1985-2006). BMI at year 0 was associated positively and linearly with CAC at year 20; however, the association of BMI with year 20 CAC became progressively U-shaped in subsequent examinations (years 10, 15, and 20). To understand the deepening U shape, the authors modeled year 20 BMI and its history using 3 indices: year 0 BMI, linear slope of BMI during 20 years, and BMI fluctuation during 20 years. In models including these 3 terms, year 0 BMI was associated positively with CAC, as was BMI fluctuation. However, adjusted odds ratios across quintiles of BMI slope (vs. the lowest quintile) were 0.7, 0.4, 0.5, and 0.4 (P(trend) < 0.01), suggesting higher risk of CAC with weight loss, plateauing after moderate weight gain. In contrast, IMT was associated positively with BMI at all examinations and with 20-year BMI slope and was unassociated with BMI fluctuation. Surprisingly, CAC risk was higher with BMI loss and lower with BMI gain, whereas associations with IMT were as expected. | lld:pubmed |
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| pubmed-article:20519263 | pubmed:language | eng | lld:pubmed |
| pubmed-article:20519263 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20519263 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:20519263 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:20519263 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:20519263 | pubmed:issn | 1476-6256 | lld:pubmed |
| pubmed-article:20519263 | pubmed:author | pubmed-author:HolvoetPaulP | lld:pubmed |
| pubmed-article:20519263 | pubmed:author | pubmed-author:JacobsDavid... | lld:pubmed |
| pubmed-article:20519263 | pubmed:author | pubmed-author:SteffesMichae... | lld:pubmed |
| pubmed-article:20519263 | pubmed:author | pubmed-author:LewisCora ECE | lld:pubmed |
| pubmed-article:20519263 | pubmed:author | pubmed-author:LeeDuk-HeeDH | lld:pubmed |
| pubmed-article:20519263 | pubmed:author | pubmed-author:GrossMyronM | lld:pubmed |
| pubmed-article:20519263 | pubmed:author | pubmed-author:KiefeCatarina... | lld:pubmed |
| pubmed-article:20519263 | pubmed:author | pubmed-author:ParkKyongK | lld:pubmed |
| pubmed-article:20519263 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:20519263 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:20519263 | pubmed:volume | 172 | lld:pubmed |
| pubmed-article:20519263 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:20519263 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:20519263 | pubmed:pagination | 180-9 | lld:pubmed |
| pubmed-article:20519263 | pubmed:dateRevised | 2011-8-1 | lld:pubmed |
| pubmed-article:20519263 | pubmed:meshHeading | pubmed-meshheading:20519263... | lld:pubmed |
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| pubmed-article:20519263 | pubmed:meshHeading | pubmed-meshheading:20519263... | lld:pubmed |
| pubmed-article:20519263 | pubmed:meshHeading | pubmed-meshheading:20519263... | lld:pubmed |
| pubmed-article:20519263 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:20519263 | pubmed:articleTitle | Differential associations of weight dynamics with coronary artery calcium versus common carotid artery intima-media thickness: The CARDIA Study. | lld:pubmed |
| pubmed-article:20519263 | pubmed:affiliation | Department of Preventive Medicine, Kyungpook National University, Daegu, South Korea. | lld:pubmed |
| pubmed-article:20519263 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:20519263 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:20519263 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
