Brain connectivity is not only lower but different in schizophrenia: a combined anatomical and functional approach.

Source:http://linkedlifedata.com/resource/pubmed/id/20497901

Biol. Psychiatry 2010 Jul 1 68 1 61-9

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Authors

Skudlarski P, Anderson K, Calhoun VD, Stevens MC, Pearlson G, Jagannathan K, Skudlarska BA

Affiliation

Olin Neuropsychiatry Research Center, Institute of Living, Hartford Hospital, Hartford, Connecticut 06106, USA. pawel.skudlarski@yale.edu

Abstract

Schizophrenia is hypothesized to involve disordered connectivity between brain regions. Currently, there are no direct measures of brain connectivity; functional and structural connectivity used separately provide only limited insight. Simultaneous measure of anatomical and functional connectivity and its interactions allow for better understanding of schizophrenia-related alternations in brain connectivity.

PMID
20497901

Publication types

Research Support, N.I.H., Extramural