| pubmed-article:20495990 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:20495990 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:20495990 | lifeskim:mentions | umls-concept:C0087111 | lld:lifeskim |
| pubmed-article:20495990 | lifeskim:mentions | umls-concept:C0936148 | lld:lifeskim |
| pubmed-article:20495990 | lifeskim:mentions | umls-concept:C0038951 | lld:lifeskim |
| pubmed-article:20495990 | lifeskim:mentions | umls-concept:C0442967 | lld:lifeskim |
| pubmed-article:20495990 | pubmed:issue | 8 | lld:pubmed |
| pubmed-article:20495990 | pubmed:dateCreated | 2010-7-29 | lld:pubmed |
| pubmed-article:20495990 | pubmed:abstractText | While a paediatric dosage has not been defined, posaconazole is occasionally being used in children. We conducted a multicentre retrospective survey and identified 15 patients (median age 10 years [range 3.6-17.5]) who received posaconazole salvage therapy for proven (9 patients) or probable (6 patients) invasive fungal infections. Posaconazole was administered for a median of 32 days (range 4-262) at a median dosage of 21 mg/kg (range 4.8-33.3). None of the patients discontinued therapy due to adverse events, which were mostly mild and observed in 11 patients. Complete or partial responses were observed in 4/7 patients with zygomycosis, 3/4 patients with invasive mould infection, 1/2 patients with invasive aspergillosis and 1/2 patients with chronic disseminated candidiasis. We conclude from the data that posaconazole displays favourable safety and tolerance and may be useful for management of individual paediatric patients with invasive infections. | lld:pubmed |
| pubmed-article:20495990 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20495990 | pubmed:language | eng | lld:pubmed |
| pubmed-article:20495990 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20495990 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:20495990 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20495990 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20495990 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20495990 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:20495990 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:20495990 | pubmed:issn | 1435-4373 | lld:pubmed |
| pubmed-article:20495990 | pubmed:author | pubmed-author:ScholzJJ | lld:pubmed |
| pubmed-article:20495990 | pubmed:author | pubmed-author:WagnerH JHJ | lld:pubmed |
| pubmed-article:20495990 | pubmed:author | pubmed-author:PhillipsRR | lld:pubmed |
| pubmed-article:20495990 | pubmed:author | pubmed-author:GrollA HAH | lld:pubmed |
| pubmed-article:20495990 | pubmed:author | pubmed-author:LehrnbecherTT | lld:pubmed |
| pubmed-article:20495990 | pubmed:author | pubmed-author:GruhnBB | lld:pubmed |
| pubmed-article:20495990 | pubmed:author | pubmed-author:KontnyUU | lld:pubmed |
| pubmed-article:20495990 | pubmed:author | pubmed-author:LüerSS | lld:pubmed |
| pubmed-article:20495990 | pubmed:author | pubmed-author:GarbinoJJ | lld:pubmed |
| pubmed-article:20495990 | pubmed:author | pubmed-author:WieselTT | lld:pubmed |
| pubmed-article:20495990 | pubmed:author | pubmed-author:DuerkenMM | lld:pubmed |
| pubmed-article:20495990 | pubmed:author | pubmed-author:AttarbaschiAA | lld:pubmed |
| pubmed-article:20495990 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:20495990 | pubmed:volume | 29 | lld:pubmed |
| pubmed-article:20495990 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:20495990 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:20495990 | pubmed:pagination | 1043-5 | lld:pubmed |
| pubmed-article:20495990 | pubmed:dateRevised | 2011-4-19 | lld:pubmed |
| pubmed-article:20495990 | pubmed:meshHeading | pubmed-meshheading:20495990... | lld:pubmed |
| pubmed-article:20495990 | pubmed:meshHeading | pubmed-meshheading:20495990... | lld:pubmed |
| pubmed-article:20495990 | pubmed:meshHeading | pubmed-meshheading:20495990... | lld:pubmed |
| pubmed-article:20495990 | pubmed:meshHeading | pubmed-meshheading:20495990... | lld:pubmed |
| pubmed-article:20495990 | pubmed:meshHeading | pubmed-meshheading:20495990... | lld:pubmed |
| pubmed-article:20495990 | pubmed:meshHeading | pubmed-meshheading:20495990... | lld:pubmed |
| pubmed-article:20495990 | pubmed:meshHeading | pubmed-meshheading:20495990... | lld:pubmed |
| pubmed-article:20495990 | pubmed:meshHeading | pubmed-meshheading:20495990... | lld:pubmed |
| pubmed-article:20495990 | pubmed:meshHeading | pubmed-meshheading:20495990... | lld:pubmed |
| pubmed-article:20495990 | pubmed:meshHeading | pubmed-meshheading:20495990... | lld:pubmed |
| pubmed-article:20495990 | pubmed:meshHeading | pubmed-meshheading:20495990... | lld:pubmed |
| pubmed-article:20495990 | pubmed:meshHeading | pubmed-meshheading:20495990... | lld:pubmed |
| pubmed-article:20495990 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:20495990 | pubmed:articleTitle | Posaconazole salvage treatment in paediatric patients: a multicentre survey. | lld:pubmed |
| pubmed-article:20495990 | pubmed:affiliation | Paediatric Haematology and Oncology, Children's Hospital III, Johann Wolfgang Goethe University, Theodor-Stern-Kai 7, Frankfurt, Germany. Thomas.Lehrnbecher@kgu.de | lld:pubmed |
| pubmed-article:20495990 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:20495990 | pubmed:publicationType | Multicenter Study | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:20495990 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:20495990 | lld:pubmed |
