| pubmed-article:20490545 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:20490545 | lifeskim:mentions | umls-concept:C0003467 | lld:lifeskim |
| pubmed-article:20490545 | lifeskim:mentions | umls-concept:C0011570 | lld:lifeskim |
| pubmed-article:20490545 | pubmed:issue | 5-6 | lld:pubmed |
| pubmed-article:20490545 | pubmed:dateCreated | 2010-6-17 | lld:pubmed |
| pubmed-article:20490545 | pubmed:abstractText | We review the literature on interoception as it relates to depression and anxiety, with a focus on belief, and alliesthesia. The connection between increased but noisy afferent interoceptive input, self-referential and belief-based states, and top-down modulation of poorly predictive signals is integrated into a neuroanatomical and processing model for depression and anxiety. The advantage of this conceptualization is the ability to specifically examine the interface between basic interoception, self-referential belief-based states, and enhanced top-down modulation to attenuate poor predictability. We conclude that depression and anxiety are not simply interoceptive disorders but are altered interoceptive states as a consequence of noisily amplified self-referential interoceptive predictive belief states. | lld:pubmed |
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