Linked Life Data

20488763

Source:http://linkedlifedata.com/resource/pubmed/id/20488763

Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:20488763rdf:typepubmed:Citationlld:pubmed
pubmed-article:20488763lifeskim:mentionsumls-concept:C0026809lld:lifeskim
pubmed-article:20488763lifeskim:mentionsumls-concept:C0039003lld:lifeskim
pubmed-article:20488763lifeskim:mentionsumls-concept:C0004927lld:lifeskim
pubmed-article:20488763lifeskim:mentionsumls-concept:C0015259lld:lifeskim
pubmed-article:20488763lifeskim:mentionsumls-concept:C0392756lld:lifeskim
pubmed-article:20488763lifeskim:mentionsumls-concept:C1314939lld:lifeskim
pubmed-article:20488763lifeskim:mentionsumls-concept:C0231449lld:lifeskim
pubmed-article:20488763lifeskim:mentionsumls-concept:C0205752lld:lifeskim
pubmed-article:20488763pubmed:issue12lld:pubmed
pubmed-article:20488763pubmed:dateCreated2010-12-1lld:pubmed
pubmed-article:20488763pubmed:abstractTextThe present study examined the hyponociceptive effect of swimming exercise in a chemical behavioral model of nociception and the mechanisms involved in this effect. Male mice were submitted to swimming sessions (30 min/d for 5 days). Twenty-four hours after the last session, we noticed that swimming exercise decreased the number of abdominal constriction responses caused by acetic acid compared with the nonexercised group. The hyponociception caused by exercise in the acetic acid test was significantly attenuated by intraperitoneal (i.p.) pretreatment of mice with naloxone (a nonselective opioid receptor antagonist, 1 mg/kg), ?-chlorophenylalanine methyl ester (PCPA, an inhibitor of serotonin synthesis, 100 mg/kg once a day for 4 consecutive days), and by bilateral adrenalectomy. Collectively, the present results provide experimental evidences indicating for the first time that high-intensity extended swimming exercise reduces pain-related behavior in mice. The mechanisms involve an interaction with opioid and serotonin systems. Furthermore, endogenous opioids released by adrenal glands probably are involved in this effect. PERSPECTIVE: Our results indicate that high-intensity extended exercise endogenously controls acute pain by activation of opioidergic and serotonergic pathways. Furthermore, these results support the use of exercise as a nonpharmacological approach for the management of acute pain.lld:pubmed
pubmed-article:20488763pubmed:languageenglld:pubmed
pubmed-article:20488763pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:20488763pubmed:citationSubsetIMlld:pubmed
pubmed-article:20488763pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:20488763pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:20488763pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:20488763pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:20488763pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:20488763pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:20488763pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:20488763pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:20488763pubmed:statusMEDLINElld:pubmed
pubmed-article:20488763pubmed:monthDeclld:pubmed
pubmed-article:20488763pubmed:issn1528-8447lld:pubmed
pubmed-article:20488763pubmed:authorpubmed-author:SantosAdair...lld:pubmed
pubmed-article:20488763pubmed:authorpubmed-author:GadottiViníci...lld:pubmed
pubmed-article:20488763pubmed:authorpubmed-author:MarconRodrigo...lld:pubmed
pubmed-article:20488763pubmed:authorpubmed-author:MartinsDaniel...lld:pubmed
pubmed-article:20488763pubmed:authorpubmed-author:Mazzardo-Mart...lld:pubmed
pubmed-article:20488763pubmed:authorpubmed-author:Dos...lld:pubmed
pubmed-article:20488763pubmed:authorpubmed-author:SpeckhannBren...lld:pubmed
pubmed-article:20488763pubmed:authorpubmed-author:SigwaltAndré...lld:pubmed
pubmed-article:20488763pubmed:authorpubmed-author:GuglielmoLuiz...lld:pubmed
pubmed-article:20488763pubmed:copyrightInfoCopyright © 2010 American Pain Society. Published by Elsevier Inc. All rights reserved.lld:pubmed
pubmed-article:20488763pubmed:issnTypeElectroniclld:pubmed
pubmed-article:20488763pubmed:volume11lld:pubmed
pubmed-article:20488763pubmed:ownerNLMlld:pubmed
pubmed-article:20488763pubmed:authorsCompleteYlld:pubmed
pubmed-article:20488763pubmed:pagination1384-93lld:pubmed
pubmed-article:20488763pubmed:meshHeadingpubmed-meshheading:20488763...lld:pubmed
pubmed-article:20488763pubmed:meshHeadingpubmed-meshheading:20488763...lld:pubmed
pubmed-article:20488763pubmed:meshHeadingpubmed-meshheading:20488763...lld:pubmed
pubmed-article:20488763pubmed:meshHeadingpubmed-meshheading:20488763...lld:pubmed
pubmed-article:20488763pubmed:meshHeadingpubmed-meshheading:20488763...lld:pubmed
pubmed-article:20488763pubmed:meshHeadingpubmed-meshheading:20488763...lld:pubmed
pubmed-article:20488763pubmed:meshHeadingpubmed-meshheading:20488763...lld:pubmed
pubmed-article:20488763pubmed:meshHeadingpubmed-meshheading:20488763...lld:pubmed
pubmed-article:20488763pubmed:meshHeadingpubmed-meshheading:20488763...lld:pubmed
pubmed-article:20488763pubmed:meshHeadingpubmed-meshheading:20488763...lld:pubmed
pubmed-article:20488763pubmed:meshHeadingpubmed-meshheading:20488763...lld:pubmed
pubmed-article:20488763pubmed:meshHeadingpubmed-meshheading:20488763...lld:pubmed
pubmed-article:20488763pubmed:meshHeadingpubmed-meshheading:20488763...lld:pubmed
pubmed-article:20488763pubmed:meshHeadingpubmed-meshheading:20488763...lld:pubmed
pubmed-article:20488763pubmed:year2010lld:pubmed
pubmed-article:20488763pubmed:articleTitleHigh-intensity extended swimming exercise reduces pain-related behavior in mice: involvement of endogenous opioids and the serotonergic system.lld:pubmed
pubmed-article:20488763pubmed:affiliationDepartamento de Ciências Fisiológicas, Centro de Ciências Biológicas, Universidade, Federal de Santa Catarina, Campus Universitário, Trindade, Florianópolis, SC, Brazil.lld:pubmed
pubmed-article:20488763pubmed:publicationTypeJournal Articlelld:pubmed