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pubmed-article:20478057pubmed:abstractTextThe sole effective option for patients with advanced HCC is sorafenib and there is an urgent need to develop new therapeutic approaches. Immunotherapy is a promising option that deserves major investigation. In this open label, single arm clinical trial, we analyzed the effect of a low dose cyclophosphamide treatment in combination with a telomerase peptide (GV1001) vaccination in patients with advanced HCC.lld:pubmed
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pubmed-article:20478057pubmed:articleTitleA phase II open label trial evaluating safety and efficacy of a telomerase peptide vaccination in patients with advanced hepatocellular carcinoma.lld:pubmed
pubmed-article:20478057pubmed:affiliationDepartment of Gastroenterology, Hannover Medical School, Carl Neuberg Strasse 1, 30625 Hannover, Germany. tim.greten@nih.govlld:pubmed
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