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pubmed-article:20459660pubmed:abstractTextThe Y chromosome of mammals is particularly prone to accumulate genes related to male fertility. However, the high rate of molecular evolution on this chromosome predicts reduced power to the across-species comparative approach in identifying male-specific genes that are essential for sperm production in humans. We performed a comprehensive analysis of expression of Y-linked transcripts and their X homologues in several human tissues, and in biopsies of infertile patients, in an attempt to identify new testis-specific genes involved in human spermatogenesis.lld:pubmed
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pubmed-article:20459660pubmed:articleTitleThe human RPS4 paralogue on Yq11.223 encodes a structurally conserved ribosomal protein and is preferentially expressed during spermatogenesis.lld:pubmed
pubmed-article:20459660pubmed:affiliationInstituto de Patologia e Imunologia Molecular da Universidade do Porto, Portugal. alopes@ipatimup.ptlld:pubmed
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