pubmed-article:20448214 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:20448214 | lifeskim:mentions | umls-concept:C0018787 | lld:lifeskim |
pubmed-article:20448214 | lifeskim:mentions | umls-concept:C0037052 | lld:lifeskim |
pubmed-article:20448214 | lifeskim:mentions | umls-concept:C0026882 | lld:lifeskim |
pubmed-article:20448214 | lifeskim:mentions | umls-concept:C0221099 | lld:lifeskim |
pubmed-article:20448214 | lifeskim:mentions | umls-concept:C1419864 | lld:lifeskim |
pubmed-article:20448214 | lifeskim:mentions | umls-concept:C0597484 | lld:lifeskim |
pubmed-article:20448214 | lifeskim:mentions | umls-concept:C0439799 | lld:lifeskim |
pubmed-article:20448214 | lifeskim:mentions | umls-concept:C1704666 | lld:lifeskim |
pubmed-article:20448214 | lifeskim:mentions | umls-concept:C1517892 | lld:lifeskim |
pubmed-article:20448214 | lifeskim:mentions | umls-concept:C0598002 | lld:lifeskim |
pubmed-article:20448214 | lifeskim:mentions | umls-concept:C0208973 | lld:lifeskim |
pubmed-article:20448214 | pubmed:issue | 1 | lld:pubmed |
pubmed-article:20448214 | pubmed:dateCreated | 2010-7-9 | lld:pubmed |
pubmed-article:20448214 | pubmed:abstractText | Familial sick sinus syndrome (SSS) has been linked to loss-of-function mutations of the SCN5A gene, which result in decreased inward Na(+) current, I(Na). However, the functional role of I(Na) in cardiac pacemaking is controversial, and mechanistic links between mutations and sinus node dysfunction in SSS are unclear. Objective: To determine mechanisms by which the SCN5A mutations impair cardiac pacemaking. | lld:pubmed |
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pubmed-article:20448214 | pubmed:language | eng | lld:pubmed |
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pubmed-article:20448214 | pubmed:citationSubset | IM | lld:pubmed |
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pubmed-article:20448214 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:20448214 | pubmed:month | Jul | lld:pubmed |
pubmed-article:20448214 | pubmed:issn | 1524-4571 | lld:pubmed |
pubmed-article:20448214 | pubmed:author | pubmed-author:MetzS HSH | lld:pubmed |
pubmed-article:20448214 | pubmed:author | pubmed-author:BoyettMark... | lld:pubmed |
pubmed-article:20448214 | pubmed:author | pubmed-author:HancoxJules... | lld:pubmed |
pubmed-article:20448214 | pubmed:author | pubmed-author:ZhangHengguiH | lld:pubmed |
pubmed-article:20448214 | pubmed:author | pubmed-author:InadaShinS | lld:pubmed |
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pubmed-article:20448214 | pubmed:issnType | Electronic | lld:pubmed |
pubmed-article:20448214 | pubmed:day | 9 | lld:pubmed |
pubmed-article:20448214 | pubmed:volume | 107 | lld:pubmed |
pubmed-article:20448214 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:20448214 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:20448214 | pubmed:pagination | 126-37 | lld:pubmed |
pubmed-article:20448214 | pubmed:dateRevised | 2011-8-1 | lld:pubmed |
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pubmed-article:20448214 | pubmed:year | 2010 | lld:pubmed |
pubmed-article:20448214 | pubmed:articleTitle | Mechanistic links between Na+ channel (SCN5A) mutations and impaired cardiac pacemaking in sick sinus syndrome. | lld:pubmed |
pubmed-article:20448214 | pubmed:affiliation | Biological Physics Group, School of Physics and Astronomy, University of Manchester, Manchester M13 9PL, United Kingdom. | lld:pubmed |
pubmed-article:20448214 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:20448214 | pubmed:publicationType | Comparative Study | lld:pubmed |
pubmed-article:20448214 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
entrez-gene:100009516 | entrezgene:pubmed | pubmed-article:20448214 | lld:entrezgene |
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