pubmed-article:20438503 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:20438503 | lifeskim:mentions | umls-concept:C0024554 | lld:lifeskim |
pubmed-article:20438503 | lifeskim:mentions | umls-concept:C0037993 | lld:lifeskim |
pubmed-article:20438503 | lifeskim:mentions | umls-concept:C0806987 | lld:lifeskim |
pubmed-article:20438503 | lifeskim:mentions | umls-concept:C1704632 | lld:lifeskim |
pubmed-article:20438503 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
pubmed-article:20438503 | lifeskim:mentions | umls-concept:C0871261 | lld:lifeskim |
pubmed-article:20438503 | lifeskim:mentions | umls-concept:C0334094 | lld:lifeskim |
pubmed-article:20438503 | lifeskim:mentions | umls-concept:C0332281 | lld:lifeskim |
pubmed-article:20438503 | lifeskim:mentions | umls-concept:C0087163 | lld:lifeskim |
pubmed-article:20438503 | lifeskim:mentions | umls-concept:C1515670 | lld:lifeskim |
pubmed-article:20438503 | lifeskim:mentions | umls-concept:C2911692 | lld:lifeskim |
pubmed-article:20438503 | lifeskim:mentions | umls-concept:C1706817 | lld:lifeskim |
pubmed-article:20438503 | lifeskim:mentions | umls-concept:C1521761 | lld:lifeskim |
pubmed-article:20438503 | lifeskim:mentions | umls-concept:C1554183 | lld:lifeskim |
pubmed-article:20438503 | pubmed:issue | 2 | lld:pubmed |
pubmed-article:20438503 | pubmed:dateCreated | 2010-5-4 | lld:pubmed |
pubmed-article:20438503 | pubmed:abstractText | The effect of L-carnitine supplementation on mitogen (concanavalin A, Con A) induced proliferation of mononuclear cells (MNC) in the spleen was investigated in broiler chickens at different ages. Day-old chickens were fed a diet supplemented with or without L-carnitine (100 ppm) for 24 days. The carnitine-supplemented group showed greater proliferation of MNC in the spleen in response to Con A than that of the control group at 24 days of age. In addition, at 24 days of age the carnitine-supplemented group showed higher expression of interleukin (IL)-2 and interferon (IFN)-gamma mRNA, but lower expression of inducible nitric oxide synthase (iNOS) in the Con A-stimulated splenic MNC than the control group. The enhancement effect of L-carnitine on MNC proliferation and IL-2 mRNA expression was not found in chicks at 14 days of age. Addition of L-carnitine (50 nmol/mL) to the culture medium enhanced proliferation and IL-2 mRNA expression of splenic MNC obtained from 24-day-old but not from 14-day-old broiler chickens. The results suggest that L-carnitine is capable of enhancing MNC proliferation in broiler chickens at 24 days of age partly through increasing IL-2 and IFN-gamma production and decreasing NO production. | lld:pubmed |
pubmed-article:20438503 | pubmed:language | eng | lld:pubmed |
pubmed-article:20438503 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20438503 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:20438503 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20438503 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20438503 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20438503 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20438503 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20438503 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20438503 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:20438503 | pubmed:month | Apr | lld:pubmed |
pubmed-article:20438503 | pubmed:issn | 1740-0929 | lld:pubmed |
pubmed-article:20438503 | pubmed:author | pubmed-author:AkibaYukioY | lld:pubmed |
pubmed-article:20438503 | pubmed:author | pubmed-author:TakahashiKazu... | lld:pubmed |
pubmed-article:20438503 | pubmed:author | pubmed-author:KitanoAyumiA | lld:pubmed |
pubmed-article:20438503 | pubmed:issnType | Electronic | lld:pubmed |
pubmed-article:20438503 | pubmed:volume | 81 | lld:pubmed |
pubmed-article:20438503 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:20438503 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:20438503 | pubmed:pagination | 215-22 | lld:pubmed |
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pubmed-article:20438503 | pubmed:year | 2010 | lld:pubmed |
pubmed-article:20438503 | pubmed:articleTitle | Effect of L-carnitine on proliferative response and mRNA expression of some of its associated factors in splenic mononuclear cells of male broiler chicks. | lld:pubmed |
pubmed-article:20438503 | pubmed:affiliation | Department of Animal Science, Faculty of Agriculture, Tohoku University, Aoba, Sendai, Japan. taka@bios.tohoku.ac.jp | lld:pubmed |
pubmed-article:20438503 | pubmed:publicationType | Journal Article | lld:pubmed |