| pubmed-article:20438364 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:20438364 | lifeskim:mentions | umls-concept:C0043210 | lld:lifeskim |
| pubmed-article:20438364 | lifeskim:mentions | umls-concept:C0035647 | lld:lifeskim |
| pubmed-article:20438364 | lifeskim:mentions | umls-concept:C0153452 | lld:lifeskim |
| pubmed-article:20438364 | lifeskim:mentions | umls-concept:C0022709 | lld:lifeskim |
| pubmed-article:20438364 | lifeskim:mentions | umls-concept:C0205217 | lld:lifeskim |
| pubmed-article:20438364 | lifeskim:mentions | umls-concept:C1442161 | lld:lifeskim |
| pubmed-article:20438364 | lifeskim:mentions | umls-concept:C1882417 | lld:lifeskim |
| pubmed-article:20438364 | lifeskim:mentions | umls-concept:C0441587 | lld:lifeskim |
| pubmed-article:20438364 | pubmed:issue | 8 | lld:pubmed |
| pubmed-article:20438364 | pubmed:dateCreated | 2010-8-17 | lld:pubmed |
| pubmed-article:20438364 | pubmed:abstractText | Gall bladder cancer (GBC) is a relatively rare but highly fatal disease, particularly in North India. The angiotensin I-converting enzyme (ACE) insertion/deletion (I/D) gene polymorphism influences serum angiotensin II action, which has been associated with various malignancies. This population-based case-control study was undertaken to examine the potential association of ACE I/D variation with GBC in a North Indian population. Genotypes and allelic frequencies of the ACE I/D polymorphism (rs4646994) were determined for 233 GBC patients and 260 cancer-free controls randomly selected from the population using polymerase chain reaction. Odds ratio (OR) and 95% confidence interval were calculated in multivariate logistic regression analysis for the association of ACE polymorphism with GBC. The ACE I/D polymorphism was found to be nonsignificantly associated with an overall increased risk of GBC (OR = 1.04 and 1.38 for I/D and D/D genotypes, respectively; p(trend) = 0.375). The increased risk was predominant significantly in female cohort and nonsignificantly in GBC patients with gallstone status (OR = 1.63; p = 0.039 and OR = 1.37; p = 0.187, respectively). In summary, ACE I/D polymorphism may alter the susceptibility to GBC, especially in women. | lld:pubmed |
| pubmed-article:20438364 | pubmed:language | eng | lld:pubmed |
| pubmed-article:20438364 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20438364 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:20438364 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20438364 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:20438364 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:20438364 | pubmed:issn | 1557-7430 | lld:pubmed |
| pubmed-article:20438364 | pubmed:author | pubmed-author:MittalBalrajB | lld:pubmed |
| pubmed-article:20438364 | pubmed:author | pubmed-author:SrivastavaAnv... | lld:pubmed |
| pubmed-article:20438364 | pubmed:author | pubmed-author:SrivastavaKsh... | lld:pubmed |
| pubmed-article:20438364 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:20438364 | pubmed:volume | 29 | lld:pubmed |
| pubmed-article:20438364 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:20438364 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:20438364 | pubmed:pagination | 417-22 | lld:pubmed |
| pubmed-article:20438364 | pubmed:meshHeading | pubmed-meshheading:20438364... | lld:pubmed |
| pubmed-article:20438364 | pubmed:meshHeading | pubmed-meshheading:20438364... | lld:pubmed |
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| pubmed-article:20438364 | pubmed:meshHeading | pubmed-meshheading:20438364... | lld:pubmed |
| pubmed-article:20438364 | pubmed:meshHeading | pubmed-meshheading:20438364... | lld:pubmed |
| pubmed-article:20438364 | pubmed:meshHeading | pubmed-meshheading:20438364... | lld:pubmed |
| pubmed-article:20438364 | pubmed:meshHeading | pubmed-meshheading:20438364... | lld:pubmed |
| pubmed-article:20438364 | pubmed:meshHeading | pubmed-meshheading:20438364... | lld:pubmed |
| pubmed-article:20438364 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:20438364 | pubmed:articleTitle | Angiotensin I-converting enzyme insertion/deletion polymorphism and increased risk of gall bladder cancer in women. | lld:pubmed |
| pubmed-article:20438364 | pubmed:affiliation | Department of Genetics, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India. | lld:pubmed |
| pubmed-article:20438364 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:20438364 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:1636 | entrezgene:pubmed | pubmed-article:20438364 | lld:entrezgene |
| entrez-gene:24310 | entrezgene:pubmed | pubmed-article:20438364 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:20438364 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:20438364 | lld:entrezgene |
