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pubmed-article:20422028pubmed:abstractTextToll-like receptors (TLRs) are among the first-line sentinels for immune detection and responsiveness to pathogens. The TLR2 subfamily of TLRs (TLR1, TLR2, TLR6) form heterodimers with each other and are thus able to recognize a broad range of components from several microbes such as yeast, Gram-positive bacteria and protozoa. Until now, TLR2 activation by bacterial ligands has long been associated with pro-inflammatory cytokines but not type I interferon responses.lld:pubmed
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pubmed-article:20422028pubmed:articleTitleMurine toll-like receptor 2 activation induces type I interferon responses from endolysosomal compartments.lld:pubmed
pubmed-article:20422028pubmed:affiliationMolecular Immunology, Helmholtz Centre for Infection Research, Braunschweig, Germany.lld:pubmed
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