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pubmed-article:2039708pubmed:abstractTextLactate dehydrogenase (LDH) isoenzyme distribution was examined in 106 urine samples being tested cytologically for evidence of bladder cancer; the samples were selected to have less than 20 leucocytes and erythrocytes per high power field and the LDH pattern determined by electrophoresis. The Papanicolaou stained-smears showed 68 negative, 17 suspicious and 21 positive. The LDH M-fraction of the urinary supernatant in cytologically positive cases was significantly greater than in negative cases, although the latter included a few false negative samples. Some of the false negatives gave positive results for the LDH M-fraction; these results suggest that the determination of LDH isoenzymes in the urine is useful in diagnosing urinary tract cancers, including early stage, and for follow-up of patients with bladder cancers after surgical resection.lld:pubmed
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pubmed-article:2039708pubmed:authorpubmed-author:TakeuchiTTlld:pubmed
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pubmed-article:2039708pubmed:authorpubmed-author:FujihiroSSlld:pubmed
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pubmed-article:2039708pubmed:volume63lld:pubmed
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pubmed-article:2039708pubmed:pagination819-21lld:pubmed
pubmed-article:2039708pubmed:dateRevised2009-11-18lld:pubmed
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pubmed-article:2039708pubmed:articleTitleThe diagnostic significance of lactate dehydrogenase isoenzymes in urinary cytology.lld:pubmed
pubmed-article:2039708pubmed:affiliationDepartment of Pathology, Gifu University School of Medicine, Japan.lld:pubmed
pubmed-article:2039708pubmed:publicationTypeJournal Articlelld:pubmed