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pubmed-article:20388528pubmed:abstractTextIt is common for depression to develop after traumatic brain injury (TBI), yet despite poorer recovery, there is a lack in our understanding of whether post-TBI brain changes involved in depression are akin to those in people with depression without TBI. Modern neuroimaging has helped recognize degrees of diffuse axonal injury (DAI) as being related to extent of TBI, but its ability to predict long-term functioning is limited and has not been considered in the context of post-TBI depression. A more recent brain imaging technique (diffusion tensor imaging; DTI) can measure the integrity of white matter by measuring the directionality or anisotropy of water molecule diffusion along the axons of nerve fibers.lld:pubmed
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pubmed-article:20388528pubmed:articleTitleTraumatic brain injury, major depression, and diffusion tensor imaging: making connections.lld:pubmed
pubmed-article:20388528pubmed:affiliationMonash Alfred Psychiatry Research Centre, The Alfred and Monash University School of Psychology and Psychiatry, Melbourne Victoria, Australia. j.maller@alfred.org.aulld:pubmed
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