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pubmed-article:20373744pubmed:abstractTextTwo polyketide metabolites, nhatrangins A (1) and B (2), were isolated from a Vietnamese collection of Lyngbya majuscula. These compounds are related to the aplysiatoxin series of metabolites, which have also been isolated from this species of marine cyanobacterium. The use of 900 MHz cryoprobe NMR allowed the elucidation of the 2D structure of 1 from approximately 0.3 mg of compound. LC-MS analysis was utilized to direct the isolation of additional material as well as the isolation of 2. Conformational analysis was completed using J-based coupling constant analysis and selective NOE experiments.lld:pubmed
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pubmed-article:20373744pubmed:dateRevised2011-7-27lld:pubmed
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pubmed-article:20373744pubmed:articleTitleNhatrangins A and B, aplysiatoxin-related metabolites from the marine cyanobacterium Lyngbya majuscula from Vietnam.lld:pubmed
pubmed-article:20373744pubmed:affiliationDepartment of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, 833 S. Wood Street, Chicago, Illinois 60612, USA.lld:pubmed
pubmed-article:20373744pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:20373744pubmed:publicationTypeResearch Support, U.S. Gov't, Non-P.H.S.lld:pubmed
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