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pubmed-article:20337516pubmed:abstractTextThis review focuses on the extensive membrane and organelle rearrangements that have been observed in plant cells infected with RNA viruses. The modifications generally involve the formation of spherules, vesicles, and/or multivesicular bodies associated with various organelles such as the endoplasmic reticulum and peroxisomes. These virus-induced organelles house the viral RNA replication complex and are known as virus factories or viroplasms. Membrane and organelle alterations are attributed to the action of one or two viral proteins, which additionally act as a scaffold for the assembly of a large complex of proteins of both viral and host origin and viral RNA. Some virus factories have been shown to align with and traffic along microfilaments. In addition to viral RNA replication, the factories may be involved in other processes such as viral RNA translation and cell-to-cell virus transport. Confining the process of RNA replication to a specific location may also prevent the activation of certain host defense functions.lld:pubmed
pubmed-article:20337516pubmed:languageenglld:pubmed
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pubmed-article:20337516pubmed:statusMEDLINElld:pubmed
pubmed-article:20337516pubmed:issn0066-4286lld:pubmed
pubmed-article:20337516pubmed:authorpubmed-author:LalibertéJean...lld:pubmed
pubmed-article:20337516pubmed:authorpubmed-author:SanfaçonHélèn...lld:pubmed
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pubmed-article:20337516pubmed:volume48lld:pubmed
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pubmed-article:20337516pubmed:pagination69-91lld:pubmed
pubmed-article:20337516pubmed:dateRevised2011-9-27lld:pubmed
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pubmed-article:20337516pubmed:year2010lld:pubmed
pubmed-article:20337516pubmed:articleTitleCellular remodeling during plant virus infection.lld:pubmed
pubmed-article:20337516pubmed:affiliationINRS-Institut Armand-Frappier, Institut National de la Recherche Scientifique, Laval, Québec, Canada H7V 1B7. jean-francois.laliberte@iaf.inrs.calld:pubmed
pubmed-article:20337516pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:20337516pubmed:publicationTypeReviewlld:pubmed
pubmed-article:20337516pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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