| pubmed-article:2027778 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2027778 | lifeskim:mentions | umls-concept:C0086705 | lld:lifeskim |
| pubmed-article:2027778 | lifeskim:mentions | umls-concept:C0332221 | lld:lifeskim |
| pubmed-article:2027778 | lifeskim:mentions | umls-concept:C1523987 | lld:lifeskim |
| pubmed-article:2027778 | lifeskim:mentions | umls-concept:C1519595 | lld:lifeskim |
| pubmed-article:2027778 | lifeskim:mentions | umls-concept:C1513371 | lld:lifeskim |
| pubmed-article:2027778 | pubmed:issue | 7 | lld:pubmed |
| pubmed-article:2027778 | pubmed:dateCreated | 1991-6-11 | lld:pubmed |
| pubmed-article:2027778 | pubmed:abstractText | Synthetic transcripts of satellite 2 DNA from the newt undergo self-catalyzed cleavage in vitro. In this report we present evidence that there are at least two distinct modes of satellite 2 transcript self-cleavage. In one mode, a single cleavage domain folds into a structure which cleaves at a slow rate. This structure may be analogous to, or a variant of, the 'hammerhead' structure believed to be active during the self-cleavage of a number of infectious plant RNAs. In an alternative mode, multiple cleavage domains interact to cleave at an enhanced rate. The permutation of the repeated satellite 2 sequence determines which of these modes of cleavage will predominate, presumably by influencing the overall conformation of the RNA. We present a model for the self-processing of multimeric satellite 2 transcripts which incorporates both of these modes of self-cleavage. | lld:pubmed |
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| pubmed-article:2027778 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2027778 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2027778 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:2027778 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2027778 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:2027778 | pubmed:issn | 0305-1048 | lld:pubmed |
| pubmed-article:2027778 | pubmed:author | pubmed-author:EpsteinL MLM | lld:pubmed |
| pubmed-article:2027778 | pubmed:author | pubmed-author:Pabón-PeñaL... | lld:pubmed |
| pubmed-article:2027778 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2027778 | pubmed:day | 11 | lld:pubmed |
| pubmed-article:2027778 | pubmed:volume | 19 | lld:pubmed |
| pubmed-article:2027778 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2027778 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2027778 | pubmed:pagination | 1699-705 | lld:pubmed |
| pubmed-article:2027778 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:2027778 | pubmed:meshHeading | pubmed-meshheading:2027778-... | lld:pubmed |
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| pubmed-article:2027778 | pubmed:meshHeading | pubmed-meshheading:2027778-... | lld:pubmed |
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| pubmed-article:2027778 | pubmed:meshHeading | pubmed-meshheading:2027778-... | lld:pubmed |
| pubmed-article:2027778 | pubmed:year | 1991 | lld:pubmed |
| pubmed-article:2027778 | pubmed:articleTitle | Alternative modes of self-cleavage by newt satellite 2 transcripts. | lld:pubmed |
| pubmed-article:2027778 | pubmed:affiliation | Department of Biological Science, Florida State University, Tallahassee 32306. | lld:pubmed |
| pubmed-article:2027778 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2027778 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:2027778 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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