| pubmed-article:20226088 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:20226088 | lifeskim:mentions | umls-concept:C0302934 | lld:lifeskim |
| pubmed-article:20226088 | lifeskim:mentions | umls-concept:C0004048 | lld:lifeskim |
| pubmed-article:20226088 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:20226088 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
| pubmed-article:20226088 | lifeskim:mentions | umls-concept:C1555389 | lld:lifeskim |
| pubmed-article:20226088 | pubmed:dateCreated | 2010-4-1 | lld:pubmed |
| pubmed-article:20226088 | pubmed:abstractText | We used fullerenes, whose dispersion at the nano-level was stabilized by grinding in nitrogen gas in an agitation mill, to conduct an intratracheal instillation study and an inhalation exposure study. Fullerenes were individually dispersed in distilled water including 0.1% Tween 80, and the diameter of the fullerenes was 33 nm. These suspensions were directly injected as a solution in the intratracheal instillation study. The reference material was nickel oxide in distilled water. Wistar male rats intratracheally received a dose of 0.1 mg, 0.2 mg, or 1 mg of fullerenes and were sacrificed after 3 days, 1 week, 1 month, 3 months, and 6 months. In the inhalation study, Wistar rats were exposed to fullerene agglomerates (diameter: 96 +/- 5 nm; 0.12 +/- 0.03 mg/m3; 6 hours/days for 5 days/week) for 4 weeks and were sacrificed at 3 days, 1 month, and 3 months after the end of exposure. The inflammatory responses and gene expression of cytokine-induced neutrophil chemoattractants (CINCs) were examined in rat lungs in both studies. | lld:pubmed |
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| pubmed-article:20226088 | pubmed:language | eng | lld:pubmed |
| pubmed-article:20226088 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20226088 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:20226088 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:20226088 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:20226088 | pubmed:issn | 1743-8977 | lld:pubmed |
| pubmed-article:20226088 | pubmed:author | pubmed-author:NakanishiJunk... | lld:pubmed |
| pubmed-article:20226088 | pubmed:author | pubmed-author:MurakamiMasah... | lld:pubmed |
| pubmed-article:20226088 | pubmed:author | pubmed-author:YamamotoKazuh... | lld:pubmed |
| pubmed-article:20226088 | pubmed:author | pubmed-author:YamamotoMakot... | lld:pubmed |
| pubmed-article:20226088 | pubmed:author | pubmed-author:MorimotoYasuo... | lld:pubmed |
| pubmed-article:20226088 | pubmed:author | pubmed-author:OyabuTakakoT | lld:pubmed |
| pubmed-article:20226088 | pubmed:author | pubmed-author:TanakaIsamuI | lld:pubmed |
| pubmed-article:20226088 | pubmed:author | pubmed-author:WangWei-NingW... | lld:pubmed |
| pubmed-article:20226088 | pubmed:author | pubmed-author:FujitaKatsuhi... | lld:pubmed |
| pubmed-article:20226088 | pubmed:author | pubmed-author:UchidaKunioK | lld:pubmed |
| pubmed-article:20226088 | pubmed:author | pubmed-author:MyojoToshihik... | lld:pubmed |
| pubmed-article:20226088 | pubmed:author | pubmed-author:HirohashiMasa... | lld:pubmed |
| pubmed-article:20226088 | pubmed:author | pubmed-author:OgamiAkiraA | lld:pubmed |
| pubmed-article:20226088 | pubmed:author | pubmed-author:ShinoharaNaoh... | lld:pubmed |
| pubmed-article:20226088 | pubmed:author | pubmed-author:KadoyaChikara... | lld:pubmed |
| pubmed-article:20226088 | pubmed:author | pubmed-author:ShimadaManabu... | lld:pubmed |
| pubmed-article:20226088 | pubmed:author | pubmed-author:EndohShigehis... | lld:pubmed |
| pubmed-article:20226088 | pubmed:author | pubmed-author:TodorokiMotoi... | lld:pubmed |
| pubmed-article:20226088 | pubmed:author | pubmed-author:NishiKen-ichi... | lld:pubmed |
| pubmed-article:20226088 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:20226088 | pubmed:volume | 7 | lld:pubmed |
| pubmed-article:20226088 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:20226088 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:20226088 | pubmed:pagination | 4 | lld:pubmed |
| pubmed-article:20226088 | pubmed:dateRevised | 2010-9-30 | lld:pubmed |
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| pubmed-article:20226088 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:20226088 | pubmed:articleTitle | Inflammogenic effect of well-characterized fullerenes in inhalation and intratracheal instillation studies. | lld:pubmed |
| pubmed-article:20226088 | pubmed:affiliation | Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan. yasuom@med.uoeh-u.ac.jp | lld:pubmed |
| pubmed-article:20226088 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:20226088 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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