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pubmed-article:20221959pubmed:dateCreated2010-3-11lld:pubmed
pubmed-article:20221959pubmed:abstractTextWe recently described the neuroimaging and clinical findings in 6 children with cerebellar clefts and proposed that they result from disruptive changes following prenatal cerebellar hemorrhage. We now report an additional series of 9 patients analyzing the clinical and neuroimaging findings. The clefts were located in the left cerebellar hemisphere in 5 cases, in the right in 3, and bilaterally in one child who had bilateral cerebellar hemorrhages as a preterm infant at 30 weeks gestation. In one patient born at 24 weeks of gestation a unilateral cerebellar hemorrhage has been found at the age of 4 months. Other findings included disordered alignment of the folia and fissures, an irregular gray/white matter junction, and abnormal arborization of the white matter in all cases. Supratentorial abnormalities were found in 4 cases. All but 2 patients were born at term. We confirm the distinct neuroimaging pattern of cerebellar clefts. Considering the documented fetal cerebellar hemorrhage in our first series, we postulate that cerebellar clefts usually represent residual disruptive changes after a prenatal cerebellar hemorrhage. Exceptionally, as now documented in 2 patients, cerebellar clefts can be found after neonatal cerebellar hemorrhages in preterm infants. The short-term outcome in these children was variable.lld:pubmed
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pubmed-article:20221959pubmed:authorpubmed-author:PorettiAAlld:pubmed
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pubmed-article:20221959pubmed:authorpubmed-author:HuismanT A...lld:pubmed
pubmed-article:20221959pubmed:copyrightInfo(c) Georg Thieme Verlag KG Stuttgart . New York.lld:pubmed
pubmed-article:20221959pubmed:issnTypeElectroniclld:pubmed
pubmed-article:20221959pubmed:volume40lld:pubmed
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pubmed-article:20221959pubmed:articleTitleCerebellar cleft: confirmation of the neuroimaging pattern.lld:pubmed
pubmed-article:20221959pubmed:affiliationDepartment of Pediatric Neurology, University Children's Hospital of Zurich, Zurich, Switzerland. Andrea.Poretti@kispi.uzh.chlld:pubmed
pubmed-article:20221959pubmed:publicationTypeJournal Articlelld:pubmed