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pubmed-article:20197451pubmed:abstractTextRodent species are widely used in the testing and approval of new radiopharmaceuticals, necessitating murine phantom models. As more therapy applications are being tested in animal models, calculating accurate dose estimates for the animals themselves becomes important to explain and control potential radiation toxicity or treatment efficacy. Historically, stylized and mathematically based models have been used for establishing doses to small animals. Recently, a series of anatomically realistic human phantoms was developed using body models based on nonuniform rational B-spline. Realistic digital mouse whole-body (MOBY) and rat whole-body (ROBY) phantoms were developed on the basis of the same NURBS technology and were used in this study to facilitate dose calculations in various species of rodents.lld:pubmed
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pubmed-article:20197451pubmed:authorpubmed-author:FernaldMichae...lld:pubmed
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pubmed-article:20197451pubmed:dateRevised2010-9-1lld:pubmed
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pubmed-article:20197451pubmed:year2010lld:pubmed
pubmed-article:20197451pubmed:articleTitleRADAR realistic animal model series for dose assessment.lld:pubmed
pubmed-article:20197451pubmed:affiliationDepartment of Radiology and Radiological Sciences, Vanderbilt University, Nashville, Tennessee, USA. mary.a.emmons@vanderbilt.edulld:pubmed
pubmed-article:20197451pubmed:publicationTypeJournal Articlelld:pubmed
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