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pubmed-article:20194914pubmed:abstractTextFatigue is a common and disabling symptom in neurologic disorders including traumatic penetrating brain injury (PBI). Despite fatigue's prevalence and impact on quality of life, its pathophysiology is not understood. Studies on effort perception in healthy subjects, animal behavioral paradigms, and recent evidence in different clinical populations suggest that ventromedial prefrontal cortex could play a significant role in fatigue pathophysiology in neurologic conditions.lld:pubmed
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pubmed-article:20194914pubmed:articleTitleVentromedial prefrontal cortex modulates fatigue after penetrating traumatic brain injury.lld:pubmed
pubmed-article:20194914pubmed:affiliationCognitive Neuroscience Section, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD 20892-1440, USA.lld:pubmed
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