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pubmed-article:20190159pubmed:abstractTextPrevious studies have shown that mean 24-h GH concentrations determine plasma IGF-I levels in patients with acromegaly. However, we have recently shown that continuous GH infusion, mimicking the interpulse GH levels, was significantly more effective than the pulsatile GH administration at increasing IGF-I concentrations.lld:pubmed
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pubmed-article:20190159pubmed:articleTitleBasal, but not pulsatile, growth hormone secretion determines the ambient circulating levels of insulin-like growth factor-I.lld:pubmed
pubmed-article:20190159pubmed:affiliationDivision of Metabolism, Endocrinology, and Diabetes, Department of Neurosurgery, University of Michigan Medical Center and Veterans Affairs Medical Center, Ann Arbor, Michigan 48016, USA.lld:pubmed
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