pubmed-article:2018370 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:2018370 | lifeskim:mentions | umls-concept:C0032207 | lld:lifeskim |
pubmed-article:2018370 | lifeskim:mentions | umls-concept:C0205381 | lld:lifeskim |
pubmed-article:2018370 | lifeskim:mentions | umls-concept:C0037806 | lld:lifeskim |
pubmed-article:2018370 | lifeskim:mentions | umls-concept:C0936012 | lld:lifeskim |
pubmed-article:2018370 | pubmed:issue | 1 | lld:pubmed |
pubmed-article:2018370 | pubmed:dateCreated | 1991-5-23 | lld:pubmed |
pubmed-article:2018370 | pubmed:abstractText | Wet ashing of K562 cell suspensions by means of a sulphonitroperchloric acid digestion for electrothermal atomic absorption spectrometry of platinum has been achieved. The limit of detection was about 1 ng platinum per 10(6) cells. Platinum concentrations in K562 cells were measured after exposure to platinum coordination complexes such as cis-dichlorodiamminoplatinum (DDP) and Trans-1 diamminocyclohexanooxalatoplatinum (1-OHP). Cell linked platinum was measured after a 24 hours exposure to a concentration of 6.8 nM ml-1 of both forms 1-OHP and DDP (i.e. 1.3 micrograms platinum per ml). Platinum concentrations were found to be respectively (mean +/- S.D.) 14.8 +/- 2.7 and 10.0 +/- 4.0 ng platinum per 10(6) cells. These 1-OHP and DDP concentrations were cytotoxic and about twenty times the 50 percent cell growth inhibitory concentrations (0.45 nM ml-1 and 0.33 nM ml-1 respectively). | lld:pubmed |
pubmed-article:2018370 | pubmed:language | eng | lld:pubmed |
pubmed-article:2018370 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2018370 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:2018370 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2018370 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2018370 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2018370 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2018370 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2018370 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2018370 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:2018370 | pubmed:issn | 0250-7005 | lld:pubmed |
pubmed-article:2018370 | pubmed:author | pubmed-author:MillartHH | lld:pubmed |
pubmed-article:2018370 | pubmed:author | pubmed-author:TabaruHH | lld:pubmed |
pubmed-article:2018370 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:2018370 | pubmed:volume | 11 | lld:pubmed |
pubmed-article:2018370 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:2018370 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:2018370 | pubmed:pagination | 343-6 | lld:pubmed |
pubmed-article:2018370 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
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pubmed-article:2018370 | pubmed:articleTitle | Flameless atomic absorption spectrophotometry analysis of cell-linked platinum after wet ashing. | lld:pubmed |
pubmed-article:2018370 | pubmed:affiliation | Laboratoire d'Immunologie, Hôpital Robert Debré, Reims, France. | lld:pubmed |
pubmed-article:2018370 | pubmed:publicationType | Journal Article | lld:pubmed |