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pubmed-article:20178783pubmed:abstractTextThe midbrain periaqueductal grey (PAG) area is important for both pain modulation and cardiovascular control via the autonomic nervous system (ANS). While changes in blood pressure dependent upon dorsal or ventral electrode positioning have been described with PAG deep brain stimulation (DBS), little is known mechanistically about the relationships between pain and cardiovascular regulation in humans. Heart rate variability (HRV) is an established measure of cardiovascular regulation, and an index of autonomic function.lld:pubmed
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pubmed-article:20178783pubmed:articleTitleVentral periaqueductal grey stimulation alters heart rate variability in humans with chronic pain.lld:pubmed
pubmed-article:20178783pubmed:affiliationNuffield Department of Surgery, University of Oxford, Oxford, UK. eacp@eacp.co.uklld:pubmed
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