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pubmed-article:20162027pubmed:abstractTextThe aim of curative surgical oncology is to remove the primary tumour with a wide margin of normal tissue. What constitutes a sufficiently wide margin particularly in oral cancer is fundamentally unclear. The currently accepted standard is to remove the primary lesion with a 1.5-2 cm circumferential macroscopic margin. In the last ten years, anatomical considerations in the approach to primary, advanced and untreated tumours of the tongue led us to develop and improve a new surgical approach to their demolition and reconstruction. From July 1999 to July 2009, at the European Institute of Oncology in Milano, Italy, 155 patients were treated, while defining and refining the concept of compartmental tongue surgery (CTS) and its main components: 1) anatomical approach to the disease that requires removal of the primary lesion and all of the potential pathways of progression--muscular, lymphatic and vascular; 2) identification of a distinct territory at risk of metastatic representation of the disease: the parenchymal structures between the primary tumour and the cervical lymphatic chain that include the muscular (mylohyoid), neuro-vascular (lingual nerve and vein) and glandular (sublingual and submandibular) tissues; 3) preparation for a rational reconstruction in consideration of a functional defect resulting from this anatomical demolition.lld:pubmed
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pubmed-article:20162027pubmed:authorpubmed-author:CalabreseLLlld:pubmed
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pubmed-article:20162027pubmed:volume29lld:pubmed
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pubmed-article:20162027pubmed:dateRevised2010-9-30lld:pubmed
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pubmed-article:20162027pubmed:articleTitleCompartmental surgery in tongue tumours: description of a new surgical technique.lld:pubmed
pubmed-article:20162027pubmed:affiliationDepartment of Head and Neck Surgery, European Institute of Oncology, Via Ripamonti 435, Milan, Italy. luca.calabrese@ieo.itlld:pubmed
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