| pubmed-article:20142483 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:20142483 | lifeskim:mentions | umls-concept:C0153676 | lld:lifeskim |
| pubmed-article:20142483 | lifeskim:mentions | umls-concept:C1511790 | lld:lifeskim |
| pubmed-article:20142483 | lifeskim:mentions | umls-concept:C1521991 | lld:lifeskim |
| pubmed-article:20142483 | lifeskim:mentions | umls-concept:C0205369 | lld:lifeskim |
| pubmed-article:20142483 | lifeskim:mentions | umls-concept:C0024485 | lld:lifeskim |
| pubmed-article:20142483 | lifeskim:mentions | umls-concept:C0332324 | lld:lifeskim |
| pubmed-article:20142483 | pubmed:issue | 8 | lld:pubmed |
| pubmed-article:20142483 | pubmed:dateCreated | 2010-2-25 | lld:pubmed |
| pubmed-article:20142483 | pubmed:abstractText | Early and specific detection of metastatic cancer cells in the lung (the most common organ targeted by metastases) could significantly improve cancer treatment outcomes. However, the most widespread lung imaging methods use ionizing radiation and have low sensitivity and/or low specificity for cancer cells. Here we address this problem with an imaging method to detect submillimeter-sized metastases with molecular specificity. Cancer cells are targeted by iron oxide nanoparticles functionalized with cancer-binding ligands, then imaged by high-resolution hyperpolarized (3)He MRI. We demonstrate in vivo detection of pulmonary micrometastates in mice injected with breast adenocarcinoma cells. The method not only holds promise for cancer imaging but more generally suggests a fundamentally unique approach to molecular imaging in the lungs. | lld:pubmed |
| pubmed-article:20142483 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:language | eng | lld:pubmed |
| pubmed-article:20142483 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:20142483 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20142483 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:20142483 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:20142483 | pubmed:issn | 1091-6490 | lld:pubmed |
| pubmed-article:20142483 | pubmed:author | pubmed-author:LeuschnerCaro... | lld:pubmed |
| pubmed-article:20142483 | pubmed:author | pubmed-author:MaronpotRober... | lld:pubmed |
| pubmed-article:20142483 | pubmed:author | pubmed-author:FubaraBomaB | lld:pubmed |
| pubmed-article:20142483 | pubmed:author | pubmed-author:WarrenWarren... | lld:pubmed |
| pubmed-article:20142483 | pubmed:author | pubmed-author:DriehuysBasti... | lld:pubmed |
| pubmed-article:20142483 | pubmed:author | pubmed-author:KumarChalla... | lld:pubmed |
| pubmed-article:20142483 | pubmed:author | pubmed-author:BrancaRosa... | lld:pubmed |
| pubmed-article:20142483 | pubmed:author | pubmed-author:ClevelandZack... | lld:pubmed |
| pubmed-article:20142483 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:20142483 | pubmed:day | 23 | lld:pubmed |
| pubmed-article:20142483 | pubmed:volume | 107 | lld:pubmed |
| pubmed-article:20142483 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:20142483 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:20142483 | pubmed:pagination | 3693-7 | lld:pubmed |
| pubmed-article:20142483 | pubmed:dateRevised | 2011-4-25 | lld:pubmed |
| pubmed-article:20142483 | pubmed:meshHeading | pubmed-meshheading:20142483... | lld:pubmed |
| pubmed-article:20142483 | pubmed:meshHeading | pubmed-meshheading:20142483... | lld:pubmed |
| pubmed-article:20142483 | pubmed:meshHeading | pubmed-meshheading:20142483... | lld:pubmed |
| pubmed-article:20142483 | pubmed:meshHeading | pubmed-meshheading:20142483... | lld:pubmed |
| pubmed-article:20142483 | pubmed:meshHeading | pubmed-meshheading:20142483... | lld:pubmed |
| pubmed-article:20142483 | pubmed:meshHeading | pubmed-meshheading:20142483... | lld:pubmed |
| pubmed-article:20142483 | pubmed:meshHeading | pubmed-meshheading:20142483... | lld:pubmed |
| pubmed-article:20142483 | pubmed:meshHeading | pubmed-meshheading:20142483... | lld:pubmed |
| pubmed-article:20142483 | pubmed:meshHeading | pubmed-meshheading:20142483... | lld:pubmed |
| pubmed-article:20142483 | pubmed:meshHeading | pubmed-meshheading:20142483... | lld:pubmed |
| pubmed-article:20142483 | pubmed:meshHeading | pubmed-meshheading:20142483... | lld:pubmed |
| pubmed-article:20142483 | pubmed:meshHeading | pubmed-meshheading:20142483... | lld:pubmed |
| pubmed-article:20142483 | pubmed:meshHeading | pubmed-meshheading:20142483... | lld:pubmed |
| pubmed-article:20142483 | pubmed:meshHeading | pubmed-meshheading:20142483... | lld:pubmed |
| pubmed-article:20142483 | pubmed:year | 2010 | lld:pubmed |
